Study of Biomarkers of Heat Tolerance and Recovery During Ultra-endurance Exercise
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 11
- 试验地点
- 1
- 主要终点
- Degree of correlation between core temperature measured at the end of passive heat exposure and that measured at the end of active heat exposure
研究概览
简要总结
Military personnel are called upon to serve in hot, dry or humid climates, which places great demands on their ability to tolerate heat. Induced heat stress can impair performance and lead to pathologies. Faced with the challenges of global warming, this issue is becoming increasingly important in the practice of sport. While hyperthermia is known to impair endurance performance, the underlying thermophysiological responses and regulatory mechanisms during prolonged exercise remain poorly understood. The effects of hyperthermia on mental performance raise questions about the degradation of interoceptive capacities and the deleterious impact on behavioral regulation, an important component of thermal risk management in ultra-endurance exercise. What's more, despite the muscular and hydromineral consequences (rhabdomyolysis, renal failure, dehydration) of prolonged exercise, few data are available on recovery kinetics. A better understanding of the factors conditioning recovery quality could help limit the deleterious consequences of ultra-endurance exercise.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 37 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy individuals
- •BMI between 18 and 25 kg/m2
- •Weight ≥ 51 kg
- •Minimum training volume 6 days/7, aerobic
- •Participation in a running competition ≥ 6hours
- •Having given informed consent
排除标准
- •Presence or history of medical pathology
- •Presence of significant deviation from normal electrocardiogram values
- •History of heat stroke
- •Known intolerance to heat
- •Inability to swallow a capsule or refusal of rectal probe
- •Alcohol consumption exceeding the equivalent of 3 glasses of wine per week
- •Consumption of narcotics
- •Smoking > 0.5 pack of cigarettes per day
- •On usual medication
- •Pregnant or breast-feeding women
- •Protected adult, under legal protection, guardianship or curatorship, or unable to give personal written consent
结局指标
主要结局
Degree of correlation between core temperature measured at the end of passive heat exposure and that measured at the end of active heat exposure
时间窗: Through study completion (1 month)
Core temperature will be measured in every participants at the end of passive heat exposure and at the end of active heat exposure. A correlation analysis will be performed on these measurements.
次要结局
未报告次要终点
