The effect of combined vaginal misoprostol and tourniquet or tourniquet alone on reducing blood loss during abdominal myomectomy.
- Conditions
- Primary haemorrhage during myomectomy
- Registration Number
- PACTR202303468069055
- Lead Sponsor
- Deliverance Agyabeng
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 133
All reproductive-aged women with symptomatic fibroids who desire future fertility
Uterine size not exceeding 28 weeks gestation on abdominal examination
All women with symptomatic uterine fibroids who give voluntary consent tp partake in the study
Parous reproductive-aged women with symptomatic fibroids and no future fertility wishes
Peri-menopausal women with symptomatic fibroids who do not desire fertility
Women with hemoglobin level less than 10g/dl before surgery
Women with prior abdominal surgeries including Cesarean section and previous myomectomy
Women with body mass index greater than 35kg/m2, due to surgical challenges
Women who refuse blood transfusion
Women with hemoglobinopathies and coagulation disorders
Women with co-existing chronic medical conditions
Women who have allergies to prostaglandins
Women with symptoms suggestive of Covid-19 and who test positive for the virus within two weeks prior to surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the reduction in blood loss using pre-operative and post-operative hemoglobin changes between women in the treatment and control groups
- Secondary Outcome Measures
Name Time Method To determine the need for intraoperative or post-operative blood transfusion for women in both the treatment and the control groups. To assess the prevalence of adverse effects of misoprostol in the treatment group. To assess the differences in post-operative febrile morbidity, surgery duration and length of hospital stay in both the treatment and control groups