Comparison of Synchrony Between 4 NIV Ventilators
Not Applicable
Completed
- Conditions
- Respiratoy Failure Requiring NIV Treatment
- Registration Number
- NCT01615432
- Lead Sponsor
- University of Lausanne Hospitals
- Brief Summary
Comparison of the effects of 4 ventilators dedicated to NIV (2 home ventilators and 2 ventilators designed for NIV) on patient-ventilator synchrony and comfort in patients admitted in the intensive care unit for respiratory failure and treated with NIV.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 22
Inclusion Criteria
- respiratory failure
Exclusion Criteria
- Severe hypoxemia requiring an FiO2 > 0.6
- Hemodynamic instability : defined as a variation of > 20% in mean arterial pressure (MAP) and heart rate (HR) during the previous 2 hours; the need for high doses of catecholamines (namely > 0.5 mcg/kg/min) and/or the need of major volume resuscitation (more than 2 liters of fluids in 2 hours)
- Impaired consciousness or absence of patient cooperation;
- Facial or laryngeal lesions contraindicating the use of NIV;
- Poor short term prognosis.
- Age < 18 years old
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Patient-ventilator synchrony Patient-ventilator synchrony will be assessed breath by brath on the basis of airway pressure, flow and diaphragmatic electrical activity recordings.
- Secondary Outcome Measures
Name Time Method comfort of patient under NIV Patient's confort during NIV will be assessed using a visual analogic scale.
Ventilatory parameters Tidal volume, respiratory rate, inspiratory time, expiratory time and maximal and mean airway pressure will be measured from the continuous recording of airway pressure and flow.
Trial Locations
- Locations (1)
Intensive care and burn unit / CHUV
🇨ðŸ‡Lausanne, Vaud, Switzerland