Association Between Mother and Child Weight Gain: Statistical Methods With Validation
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 20,670
- Locations
- 1
- Primary Endpoint
- Obesity of the Child (in the Mother-child Pair) During the First 5 Years of the Child's Life
Study Overview
Brief Summary
Using retrospective data from the Vanderbilt University Medical Center electronic health record, the investigators will study the association between mother's weight / weight change before and during pregnancy and the development of childhood obesity up until 5 years of age.
Detailed Description
The investigators are extracting de-identified retrospective data from the Vanderbilt University Medical Center electronic health record for mother-child pairs. From this data, the investigators will study the association between mother weight change during pregnancy and the risk of her child developing obesity during the first 5 years of life. Included mothers must have at least one weight measurement and at least one height measurement; they must have at least one child with weight/length measurements at birth and one additional same day height/weight measurement at or before 5 years of age.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 0 Years to — (Child, Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Mother-child pairs in the Vanderbilt University Medical Center (VUMC) electronic health record.
- •The mothers must have at least one height measurement.
- •The mothers must also have at least one weight measurement during pregnancy.
- •The child must have birth length and weight measures and at least one same day height/weight measurement during their first 5 years of life.
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Obesity of the Child (in the Mother-child Pair) During the First 5 Years of the Child's Life
Time Frame: first 5 years of child's life
Obesity of the child is defined as having a BMI-by-age classification greater than the 95th percentile based on the US CDC percentiles.
Secondary Outcomes
No secondary outcomes reported
Investigators
Bryan Shepherd
Professor of Biostatistics
Vanderbilt University Medical Center