Psilocybin as a tool for enhancing cognitive flexibility”
- Conditions
- psilocybin, divergent thinking, neurotransmission
- Registration Number
- NL-OMON25919
- Lead Sponsor
- niversity Maastricht (UM)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
•Previous experience with a psychedelic drug, but not within the past 6 months.
•Age between 18 and 40 years
Exclusion Criteria
•History of drug addiction (determined by the medical questionnaire, drug questionnaire and medical examination)
•Previous experience of serious side effects to psychedelic drugs (anxiety or panic attacks)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To use psilocybin as a research tool in order to enhance divergent thinking, and facilitate relative goal-directed versus habitual behaviour during and after drug intoxication, and to assess whether psilocybin will deter a stress induced shift from goal directed to habitual behaviour.
- Secondary Outcome Measures
Name Time Method To assess cortical-subcortical functional connectivity alterations, as well as the relationship between metabolic activity and behavioural outcomes. Furthermore, subjective experience and drug concentration levels will be assessed in relation to the aforementioned variables.