CTRI/2025/02/080056Not yet recruitingPhase 4
A Prospective Randomized Comparision of Intravenous Paracetamol and Ibuprofen as Preemptive Analgesia in Total Laparoscopic Abdominal Hysterectomy
RNT Medical College Udaipur Rajasthan1 site in 1 country88 target enrollmentStarted: February 20, 2025Last updated:
Trial Snapshot
- Phase
- Phase 4
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 88
- Locations
- 1
- Primary Endpoint
- Post operative analgesia
Study Overview
Brief Summary
My clinical study is pre-emptive intravenous paracetamol and ibuprofen for acute post operative pain in laparoscopisc abdominal hysterectomy. We want to study comparative effect of paracetamol and ibuprofen infusion on post operative pain. Kindly consider it for CTRI registrar.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 40.00 Year(s) to 60.00 Year(s) (—)
- Sex
- Female
Inclusion Criteria
- •Patients of ASA grade I-II 2) Patients scheduled for laparoscopic abdominal hysterectomy surgeries.
Exclusion Criteria
- •Lack of patient consent 2) Drug dependence 3) History of long-term NSAIDs and opioid analgesic use 4) Patients allergic to ibuprofen and paracetamol 5) Patients with diabetes or other neuropathic diseases 6) History of gastrointestinal bleeding, peptic ulcer or inflammatory bowel disease, asthma 7) Patients with severe hepatic or renal failure 8) Patients weighing less than 40 Kg.
Outcomes
Primary Outcomes
Post operative analgesia
Time Frame: 24 hours post-operatively
Secondary Outcomes
- 1)hemodynamic changes(2)the time to first analgesic requirement and total tramadol consumption)
Investigators
Dr Ravindra Kumar Gehlot
RNT Medical college Udaipur Rajasthan
Study Sites (1)
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