跳至主要内容
临床试验/CTRI/2025/09/094050
CTRI/2025/09/094050尚未招募不适用

Comparison of two different doses of intra operative propofol infusion on post operative rescue antiemetic requiremnt after inhalational anaesthesia

Diana John1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2025年9月22日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
50
试验地点
1
主要终点
proportion of patients requiring rescue anti emetics in first four hours for PONV

研究概览

简要总结

Intra operatively patients will be administered with propofol infusion at the rate of 25 microgram per kg per minute in one group  and  50 microgram per kg per minute in the next group  and patients will be asessed for requirement of rescue antiemetics  for postoperative nausea and vomoting in the first four hours also as in intervals of zero  4 8 12 and 24 hours  using a 3point scale .where zero is no nausea or vomiting, one is only nausea, two is vomiting with or without nausea.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • ASA physical status 1 to 3 BMI 18 to 30.

排除标准

  • pregnant and lactating patients cardiac, neuro,bariatric surgeries surgical duration more than 6 hours.

结局指标

主要结局

proportion of patients requiring rescue anti emetics in first four hours for PONV

时间窗: proportion of patients requiring rescue anti emetics in first four hours for PONV

次要结局

  • total requirement of rescue antiemetics in 24 hrs post op(24 hrs post op)
  • number of patients having ponv in first 24 hrs post op(first 24 hours)
  • time to discharge from pacu as per modified aldret score more than nine(nil)

研究者

发起方
Diana John
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Diana John

Maulana azad medical college

研究点 (1)

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