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Clinical Trials/NCT04333069
NCT04333069
Unknown
Not Applicable

Outcome of Cataract Surgery in Patient With Uveitis

Assiut University0 sites50 target enrollmentApril 10, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cataract; Complicata
Sponsor
Assiut University
Enrollment
50
Primary Endpoint
final postoperative uncorrected visual acuity (UCVA)
Last Updated
6 years ago

Overview

Brief Summary

Aim of the study is to evaluate outcome of cataract surgery in different types of uveitis as regarding best corrected visual acuity (BCVA) and rate of post operative complications.

Detailed Description

Cataract is the main cause of reversible blindness in patients with uveitis. Cataract occurs in up to 50% to 70% of patients with uveitis. Preoperative complications, including anterior synechiae, posterior synechiae, and pupillary membrane formation, may increase surgical challenges. In addition, recurrent inflammation increases the incidence of postoperative complications and often affects the visual prognosis. In recent years, phacoemulsification with intra ocular lens (IOL)implantation has become the main surgical method for treating uveitis (complicated cataract), and the visual prognosis of patients who undergo this procedure is usually favorable. Surgical treatment may be effective but is associated with higher rates of complication than in non uveitic eyes. Cystoid macular edema (CME) is the most common complication cataract surgery in the general population. Although, in most cases, the macular edema is self-limited, in rare cases it can lead to long-term visual deterioration that is difficult to treat. Another common complication after cataract surgery is posterior capsule opacification (PCO) , leading to symptoms of glare or blurred vision, reduced visual acuity, or impaired posterior segment exam. Factors that are critical in the development of PCO include surgical technique, type of implanted intra ocular lens (IOL) either foldable hydrophilic acrylic, hydrophobic acrylic or silicone and postoperative control of uveitis

Registry
clinicaltrials.gov
Start Date
April 10, 2020
End Date
December 20, 2022
Last Updated
6 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mona Abdallah Abdal Razik Ahmed

Assistant lecturer at Ophthalmology departmentAssiut University Faculty of Medicine

Assiut University

Eligibility Criteria

Inclusion Criteria

  • Visually significant cataract ( means opacification of the crystalline lens adequate to interfere with vision)in patients with uveitis controlled for at least 1month.

Exclusion Criteria

  • Irreversible pathology affecting outcome e.g. macular scar ,optic atrophy, and retinal detachment.
  • Patients with active uveitis (means inflammation inside the eye).
  • Patients less than 16 years old.

Outcomes

Primary Outcomes

final postoperative uncorrected visual acuity (UCVA)

Time Frame: 6months post operative

post operative uncorrected visual acuity which mean visual acuity without spectacle correction

Final post operative best corrected visual acuity (BCVA)

Time Frame: 6months post operative

Post operative visual acuity with spectacle correction

Secondary Outcomes

  • incidence of postoperative complications(6 months post operative)
  • Reactivation of intraocular inflammation(6 months post operative)

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