Outcome of Cataract Surgery in Patient With Uveitis
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 主要终点
- final postoperative uncorrected visual acuity (UCVA)
研究概览
简要总结
Aim of the study is to evaluate outcome of cataract surgery in different types of uveitis as regarding best corrected visual acuity (BCVA) and rate of post operative complications.
详细描述
Cataract is the main cause of reversible blindness in patients with uveitis. Cataract occurs in up to 50% to 70% of patients with uveitis.
Preoperative complications, including anterior synechiae, posterior synechiae, and pupillary membrane formation, may increase surgical challenges. In addition, recurrent inflammation increases the incidence of postoperative complications and often affects the visual prognosis. In recent years, phacoemulsification with intra ocular lens (IOL)implantation has become the main surgical method for treating uveitis (complicated cataract), and the visual prognosis of patients who undergo this procedure is usually favorable.
Surgical treatment may be effective but is associated with higher rates of complication than in non uveitic eyes. Cystoid macular edema (CME) is the most common complication cataract surgery in the general population. Although, in most cases, the macular edema is self-limited, in rare cases it can lead to long-term visual deterioration that is difficult to treat.
Another common complication after cataract surgery is posterior capsule opacification (PCO) , leading to symptoms of glare or blurred vision, reduced visual acuity, or impaired posterior segment exam. Factors that are critical in the development of PCO include surgical technique, type of implanted intra ocular lens (IOL) either foldable hydrophilic acrylic, hydrophobic acrylic or silicone and postoperative control of uveitis
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 16 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Visually significant cataract ( means opacification of the crystalline lens adequate to interfere with vision)in patients with uveitis controlled for at least 1month.
排除标准
- •Irreversible pathology affecting outcome e.g. macular scar ,optic atrophy, and retinal detachment.
- •Patients with active uveitis (means inflammation inside the eye).
- •Patients less than 16 years old.
结局指标
主要结局
final postoperative uncorrected visual acuity (UCVA)
时间窗: 6months post operative
post operative uncorrected visual acuity which mean visual acuity without spectacle correction
Final post operative best corrected visual acuity (BCVA)
时间窗: 6months post operative
Post operative visual acuity with spectacle correction
次要结局
- incidence of postoperative complications(6 months post operative)
- Reactivation of intraocular inflammation(6 months post operative)
研究者
Mona Abdallah Abdal Razik Ahmed
Assistant lecturer at Ophthalmology departmentAssiut University Faculty of Medicine
Assiut University