Taste Disturbance After Middle Ear Surgery: Frequency, Duration, Influence of Chorda Tympani Injury and Quality of Life

Completed

• Conditions: Ear Middle Problems
• Interventions: Other: Questionnaire

• Registration Number: NCT04899011
• Lead Sponsor: Centre Hospitalier Universitaire de Nice

Brief Summary

Chorda tympani nerve (CTN), is a branch of nerve VII, and has two componants: taste sensation from the anterior two thirds of the tongue and salivary secretion from submandibular and sublingual salivary glands.

CTN go throw middle ear between malleus and incus. Due to it anatomic localization, CTN is frequently damage during otologic surgery.

Taste disturbance after middle ear surgery has been describe in literature but results of the various studies are very heterogenous. Moreover, there is no consensus to preserved or sacrificed a traumatize CTN.

We will use questionnaire to evaluate frequency, duration and characteristics of taste disturbance after ear surgery and the impact on the quality of life for those with symptoms.

We will evaluate the Influence of type of CTN injury on taste disturbance.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-05-19
• Study First Submitted QC: 2021-05-19
• Study First Posted: 2021-05-24
• Study Start: 2021-05-30
• Primary Completion: 2023-05-23
• Study Completion: 2023-05-23
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-05
• Last Update Posted: 2025-03-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 214

Inclusion Criteria

• Patient undergoing middle ear surgery
• Acceptation to participate
• under 18 years old, parental authorization.

Exclusion Criteria

• Taste disturbance before surgery
• Patients with guardianship or tutelage measure

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Middle ear surgery	Questionnaire	-

Primary Outcome Measures

Name	Time	Method
Frequency, duration and characteristics of taste and salivary disturbance after middle ear surgery and impact on quality of life.	1 year	Taste and salivary disturbance will be measure with questionnaire before and during 1 year after middle ear surgery

Secondary Outcome Measures

Name	Time	Method
Influence of CTN injury type: stretch versus sectionned, influence of otologic desease	1 day	Measure with surgeon questionnaire
Influence of use between endoscope or microscope surgery	1 day	Measure with surgeon questionnaire

Trial Locations

Locations (1)

CHU de Nice; 🇫🇷 Nice, France