Taste Disturbance After Middle Ear Surgery: Frequency, Duration, Influence of Chorda Tympani Injury and Quality of Life
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 214
- 试验地点
- 1
- 主要终点
- Frequency, duration and characteristics of taste and salivary disturbance after middle ear surgery and impact on quality of life.
研究概览
简要总结
Chorda tympani nerve (CTN), is a branch of nerve VII, and has two componants: taste sensation from the anterior two thirds of the tongue and salivary secretion from submandibular and sublingual salivary glands.
CTN go throw middle ear between malleus and incus. Due to it anatomic localization, CTN is frequently damage during otologic surgery.
Taste disturbance after middle ear surgery has been describe in literature but results of the various studies are very heterogenous. Moreover, there is no consensus to preserved or sacrificed a traumatize CTN.
We will use questionnaire to evaluate frequency, duration and characteristics of taste disturbance after ear surgery and the impact on the quality of life for those with symptoms.
We will evaluate the Influence of type of CTN injury on taste disturbance.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient undergoing middle ear surgery
- •Acceptation to participate
- •under 18 years old, parental authorization.
排除标准
- •Taste disturbance before surgery
- •Patients with guardianship or tutelage measure
结局指标
主要结局
Frequency, duration and characteristics of taste and salivary disturbance after middle ear surgery and impact on quality of life.
时间窗: 1 year
Taste and salivary disturbance will be measure with questionnaire before and during 1 year after middle ear surgery
次要结局
- Influence of CTN injury type: stretch versus sectionned, influence of otologic desease(1 day)
- Influence of use between endoscope or microscope surgery(1 day)