RBR-5xhygvdActive, not recruitingUnknown
Evaluation of the gut microbiota in patients with type 2 Diabetes mellitus using Semaglutide
niversidade Estadual de Campinas0 sitesStarted: August 9, 2024Last updated:
Conditions
Trial Snapshot
- Phase
- Unknown
- Status
- Active, not recruiting
- Sponsor
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18Y to 60Y (—)
Inclusion Criteria
- •Both sexes; aged between 18-60 years; individuals with type 2 Diabetes Mellitus or Pre-Diabetes; with glycated hemoglobin between 5,7% and 10%; body mass index (BMI) of 25-39.99 Kg/m²; not using medication for Diabetes or using only oral antidiabetics (metformin and/or sulfonylurea); and creatinine clearance above 30ml/min/1,73m²
Exclusion Criteria
- •Age outside the proposed range; pregnant women; smoking; patients with Type 1 Diabetes Mellitus; individuals with suspected or confirmed retinopathy; patients with chronic intestinal pathology; patients previously submitted to bariatric surgery or any surgery that results in any one of resection/injury of the nervous plexus/deviation of intestinal transit; patients with severe chronic kidney disease (creatinine clearance = 30ml/min/1.73m²); patients with moderate-intense gastroesophageal reflux disease; patients with a history of recurrent pancreatitis (because of an unclear cause, or an identified and still present cause); individuals who are using insulin; individuals who used any type of antibiotic in the last 3 months; individuals who make continuous use of probiotic drugs or proton pump inhibitors (omeprazole, pantoprazole, lansoprazole, esomeprazole, etc.); individuals who have used GLP-1 analogue drugs in the last 3 months; individuals who have a significant psychiatric disorder that may be related to the incorrect use of the medication and interfere with the results (schizophrenia, bipolar disorder, alcoholism, use of illicit substances, etc)
Investigators
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