Evaluation of the Efficacy of Panax Ginseng on Lipid Metabolism in Men and the Relationship With Sports Practice.

Early Phase 1

Completed

• Conditions: Sports Physical Therapy
• Interventions: Dietary Supplement: Panax Ginseng Supplementation; Dietary Supplement: Placebo Supplementation

• Registration Number: NCT03888196
• Lead Sponsor: Universitat de Lleida

Brief Summary

Panax Ginseng (P ginseng), C.A. Meyer, Red, Chinese or Korean ginseng is a plant from eastern Asia and is one of the most widely used herbal products in the world. P ginseng has been been used for many years for different medical therapies. Previous studies have demonstrate that P. ginseng root extract supplementation may promote fat oxidation, increase hepatic glycogen levels and produce a glycogen-sparing and antifatigue effect during exercise in swimming rats. Notwithstanding, although there is some evidence of P. ginseng effects in humans, no evidence has been obtained respect to its supplementation in human sport performance. The aim of this study is to assess the effect of P ginseng extract supplementation on the lipid metabolism and sport performance in male endurance runners. For this purpose, the effect of supplementation for 2 weeks of 500 mg/day of P. ginseng will be evaluated in a sub-maximal physical stress test. Variables of lipid metabolism, energy consumption, fatigue, and endurance will be determined.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-09-01
• Primary Completion: 2018-11-01
• Study Completion: 2019-01-15
• Study First Submitted: 2019-03-21
• Study First Submitted QC: 2019-03-22
• Study First Posted: 2019-03-25
• Status Verified: 2019-04
• Last Update Submitted: 2019-04-30
• Last Update Posted: 2019-05-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 40

Inclusion Criteria

• Athletic men of aerobic type, who participate in a supervised training as a previous step to the accomplishment of competitions
• Which their age is older than 18 years
• Training superior or equal to 3 days per week and that these workouts are stable during the intervention.

Exclusion Criteria

• Athletes with high blood pressure, with pharmacological treatment for hypercholesterolemia, diabetes, any psychiatric illness
• Athletes who practice sports without having the objective of increasing sports performance
• Athletes who use some type of ergogenic sport supplementation looking to optimize any aspect related to the sport.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intervention Group	Panax Ginseng Supplementation	500 mg/day of Panax Ginseng. 2 weeks treatment
Control Group	Placebo Supplementation	500 mg/day of Celulose. 2 weeks treatment

Primary Outcome Measures

Name	Time	Method
Change from baseline plasmatic Total Lipids at 2 weeks	2 weeks	Total Lipids in the plasma are measured in mg / dL
Change from baseline plasmatic Triglycerides at 2 weeks	2 weeks	Triglycerides in the plasma are measured in mg / dL
Change from baseline Respiratory Exchange Rate at 2 weeks	2 weeks	To quantify the amount of Oxygen consumed and the amount of carbon dioxide produced. (mL/Kg/Min)