A clinical trial to evaluate the procedure of taking patient own blood just before the start of surgery and giving it back to the patient at the end in Brain operations.
Not Applicable
Not yet recruiting
- Conditions
- Health Condition 1: D320- Benign neoplasm of cerebral meningesHealth Condition 2: Q079- Congenital malformation of nervoussystem, unspecifiedHealth Condition 3: C719- Malignant neoplasm of brain, unspecified
- Registration Number
- CTRI/2020/06/025965
- Lead Sponsor
- Dr Manbir Kaur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.All patients with American Society of Anaesthesiologist (ASA) grade 1 and grade 2
2.Patients of either sex
3.Age 18 years and above
4.Patients with haemoglobin greater than 11 g/dl
5.Patients with intracranial meningiomas and other high grade vascular tumors/ vascular malformations with estimated blood loss greater than 500 ml - 1 litre.
Exclusion Criteria
1.Patients with haemoglobin less than 11 g/dl
2.Patients with impaired renal or hepatic function
3.Pregnant women
4.Patients with deranged coagulation profile
5.Patients with coagulation disorders or patients on anticoagulants
6.Patients with a history of ischemic heart diseases, history of myocardial infarction, or patients with fixed cardiac output states.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary objective is to evaluate the difference between hemoglobin and hematocrit parameters in both the groups.Timepoint: intraoperatively, at the end of surgery and postoperatively
- Secondary Outcome Measures
Name Time Method 1)Perioperative hemodynamics in both the groups. <br/ ><br>2)Perioperative blood loss in both the groups. <br/ ><br>3)Perioperative need for allogenic blood transfusion in both the groups. <br/ ><br>4)Perioperative platelet count and coagulation parameters in both groups. <br/ ><br>5)Perioperative arterial blood gases in both groups. <br/ ><br>6)Perioperative complications in each group. <br/ ><br>7)Overall ICU stay and Length of hospital stay in each group. <br/ ><br>Timepoint: intraoperatively, at the end of surgery and postoperatively