Supine vs Prone in non-ventilated patients with respiratory failure
Phase 2
Completed
- Conditions
- Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhereHealth Condition 2: J22- Unspecified acute lower respiratory infection
- Registration Number
- CTRI/2020/12/029702
- Lead Sponsor
- Apollo Hospitals Education and Research Foundation
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
>18 years
Type 1 respiratory failure
SpO2 >92% on 4litres or more oxygen or PF ratio <300
PCO2 <45mmHg
Patients with hemodynamic shock requiring norepinephrine < 0.1 mcg/kg/min
Exclusion Criteria
<18 years
Pregnant women
PCO2 >45mmHg
Patients with hemodynamic shock requiring norepinephrine >= 0.1 mcg/kg/min
GCS <15
Patients who need immediate intubation
Spinal instability
Life threatening cardiac arrhythmias
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome measure is the proportion of patients adhering to the protocol in each groupTimepoint: 2 weeks
- Secondary Outcome Measures
Name Time Method Secondary outcome measures include total number of patients recruited per week, failure of oxygen therapy leading to escalation of respiratory support, number of hours prone and the total number of prone sessions in a day, length of stay in the ICU, hospital length of stay, mortalityTimepoint: at 2 weeks and 4 weeks