The effect of prone positioning on non-intubated patients with acute respiratory failure
- Conditions
- Diseases of th respiratory system
- Registration Number
- KCT0005258
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 92
adult patients with acute respiratory failure
- 30 minutes after applying High flow nasal cannula(FiO2 0.5, flow 50L) -> PaO2< 150?Hg, PaCO2< 50?Hg
unable to applying prone position(unstable bone fracture, sternotomy, face or chest trauma, etc)
unable to applying prone position(agitation, refuse)
head trauma, DVT, pacemaker insertion within 15 days
spinal or femur or pelvic bone fracture
arterial PaCO2 > 50mmHg
mean arterial pressure < 65mmHg
pregnant women
chest tube in anterior thorax
acute asthma aggravation
cardiogenic pulmonary edema
unable to apply prone position due to agitation, patient's refusal
intubated patients
- clinically detoriated patients
- hemodynamically unstable
- mental change (GCS < 12)
- Sx or sign of respiratory failure
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method intubation rate after 7 days
- Secondary Outcome Measures
Name Time Method ung ultrasound reaeration score;PaO2/FiO2 ratio;Mechanical ventilation (MV) duration;ventilator-free days;tracheostomy rate;ICU, 30 days, 90 days mortality;Complication related to prone positioning;sedative ???