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Effects of Brisk Walking on Overweight/Obesity Population

Not Applicable
Conditions
Obesity
Interventions
Behavioral: >10000 steps brisk walking
Registration Number
NCT03125993
Lead Sponsor
Guangdong Center for Disease Prevention and Control
Brief Summary

1.Objective

The investigators aim to determine the effect of brisk walking prescription (\> 10000 steps, \> five days, per week) on body components and metabolic risk factors among patients with overweight/obesity. The objectives are as follow:

1. The body components changes before/after the brisk walking prescription (\> 10000 steps, \> five days per week) intervention in overweight/obesity population;

2. The metabolic risk factors changes before/after the brisk walking prescription (\<10000 steps or \<five days per week) intervention in overweight/obesity population

2.Study design This study is a prospective 4-month follow-up scheme in which patients were treated with the following intervention: \> 10000 steps, \> five days, per week. For individual follow-up, body components and metabolic risk factors will be tested before and after the study. Every participants will be followed up in community visits every month.

3. Statistical analysis Statistical analysis will be performed using SPSS 16.0 version package (SPSS Inc., Chicago, IL.). Numerical data will be presented as mean ± standard deviation for normal distribution or otherwise median (interquartile range). Two-sided independent t-test is adopted for between-group comparison on end-points with normal distribution, otherwise non-parametric test. Row-Column table will be analyzed through chi-square test. P\<0.05 is taken as statistical significant.

Detailed Description

Obesity/overweight has been recognized as one of the most important global health threats worldwide, which is closely related to metabolism syndrome including insulin resistance, hypertension, dyslipidemia and hyperglycemia.

In 2013, an estimated 36.9% of men and 38.0% of women were overweight (BMI \>25 kg/m2) worldwide, with attributable fractions for CHD as high as 25% in the United States and 58% in the Asia-Pacific Region. Furthermore, a strong and continuous association between body mass index (BMI) and coronary heart disease (CHD) has been reported for values of BMI above 20kg/m2 .

Numerous studies have recognized the role of physical activity in promoting moderate weight loss, weight loss maintenance, and having broad-reaching implications for cardiovascular disease mortality indices, as well as reducing healthcare expenditures. The findings of a recent review suggest that mild-to-moderate intensity exercises that include both aerobic and resistance training result in additional metabolic benefits in people with obesity or type 2 diabetes. Although weight loss is minimal, body composition improves. Brisk walking, at an individual level, prove to be the physical activity most easy to maintain and could be progressively increased in intensity, achieving a cardiorespiratory benefit and decrease adiposity in the unfit.

Several small clinical trials reported inconsistent findings of short-term exercise programs on brisk walking among patients with overweight/obesity. However, these studies did not provide comparable indices, duration and intensity. Furthermore, the brisk walking effect of current physical activity guidelines on obesity/overweight is uncertain.

The current study aimed to evaluate the effects of brisk walking ( \> 10000 steps, \> five days, per week) on body components and metabolic risk factors among patients with overweight/obesity.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
150
Inclusion Criteria
  1. The inclusion criterion is individual with sedentary behaviors, adding any of the following behavior:

    1. individuals with BMI ≥24 kg/m2
    2. waist circumstance ≥102cm in male; waist circumstance ≥88cm in female;
    3. waist circumstance/hip circumstance>1.0 in male; waist circumstance/hip circumstance> 0.9 in female.
Exclusion Criteria
  • Participants were excluded with the presence of significant cardiac or pulmonary disease that could result in hypoxia or decreased perfusion.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
>10000 steps brisk walking>10000 steps brisk walkingThis study is a prospective 4-month follow-up scheme in which patients were treated with the following intervention: \> 10000 steps, \> five days, per week. For individual follow-up, body components and metabolic risk factors will be tested before and after the study.
Primary Outcome Measures
NameTimeMethod
BMIChange from Baseline BMI at 4 months

Body components

Secondary Outcome Measures
NameTimeMethod
abdominal circumstanceChange from abdominal circumstance at 4 months

Body components

body fat percentageChange from body fat percentage at 4 months

Body components

Systolic blood pressureChange from systolic blood pressure at 4 months

Cardiovascular risk factors

Diastolic blood pressureChange from diastolic blood pressure at 4 months

Cardiovascular risk factors

Plasma glucoseChange from Plasma glucose at 4 months

Cardiovascular risk factors

visceral fatChange from visceral fat at 4 months

Cardiovascular risk factors

visceral fat percentageChange from visceral fat percentage at 4 months

Body components

waist circumstance/hip circumstanceChange from waist circumstance/hip circumstance at 4 months

Body components

serum triglyceridesChange from serum triglycerides at 4 months

Cardiovascular risk factors

serum total cholesterolChange from serum total cholesterol at 4 months

Cardiovascular risk factors

high density lipoprotein-CChange from high density lipoprotein-C at 4 months

Cardiovascular risk factors

low density lipoprotein-CChange from low density lipoprotein-C at 4 months

Cardiovascular risk factors

heart rateChange from heart rate at 4 months

Cardiovascular risk factors

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