Comparative evaluation of the speed orthodontic tooth movement by giving high frequency and low frequency vibrations.

Phase 2

Not yet recruiting

Conditions: Patients requiring therapeutic extraction space closure during fixed orthodontic treatment.

Registration Number: CTRI/2023/07/055412

Lead Sponsor: Dr Akhil Anton Joy

Brief Summary: The duration of orthodontic treatment is animportant factor for both orthodontists and their patients. Reducingtreatment time is one of the todayâ€™s most challenging issue in orthodontics,because increased treatment duration has been associated with an increased riskof caries, periodontal problems, prolonged pain as well as a higher risk ofroot resorption. To combat this, many initiatives have been made in recentyears to accelerate orthodontic tooth movement using invasive (surgical) andnon-invasive (pharmacological and physical stimulation) approaches along withconventional orthodontic force.

Vibration has been a relatively new field ofinterest to researchers which increases the rate of orthodontic tooth movementby accelerating the periodontal and bony tissue modelling and remodellingprocesses with the advantage of minimal side effects in comparison to othermethods. Initial studies to evaluate the effect of vibration on orthodontictooth movement, which were conducted on animals, have shown promising results.Evidence from such animal studies had suggested that cells respond more rapidlyto oscillation force as compared to a constant force when they have beensubjected to multiple cyclic (vibration) forces. Osteoblasts, osteoclasts,and periodontal ligament fibroblasts are intimately involved in facilitatingtooth movement as these cell types are sensitive to perceiving and respondingto mechanical signals, and therefore, are targeted by devices that aim ataccelerating the movement of teeth.

Various commercial vibratory devices have been designed to provide a cyclicvibrational force of both low and high frequency, which can be directly used bypatients. Tooth Masseuse (111 Hz), AcceleDent (30 Hz), and Vpro5 appliances(120 Hz) have been commonly used. Few studiesusing vibratory devices in orthodontic tooth movement, low frequency devices(30 Hz; 20gf) do not promote tooth movement significantly whereas highfrequency devices (120 Hz,111Hz; 6gf,5.2gf) shortens treatment time byenhancing tooth movement. Also, in studies comparing cellular responses in highfrequency and low frequency device both caused increased cell proliferation andgene expression in osteoblasts and fibroblasts, but the response to highfrequency one was slightly greater than low frequency.Still itâ€™s a topic ofcontroversy that the rate of orthodontic tooth movement is increased more byhigh frequency vibrations or the low frequency vibrations.

Hence, this current study is done to compare therate of tooth movement with high frequency and low frequency mechanicalvibrations using customized vibratory device and to evaluate root resorption insubjects with fixed conventional orthodontic therapy.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 40

Inclusion Criteria

1.Angleâ€™s Class I bimaxillary and Angleâ€™s Class II div 1 malocclusion requiring 1st premolar extraction.
2.No systemic disease.
3.No radiographic evidence of bone loss.
4.No history of periodontal therapy.
5.No current active periodontal disease, Probing depth < 4 mm in all teeth.

Exclusion Criteria

1.Nonâ€“compliant patient, inability to maintain proper oral hygiene.
2.History of prior orthodontic treatment.
3.Long term use of antibiotics, phenytoin, cyclosporine and anti â€“ inflammatory, Systemic corticosteroids & calcium channel blockers.
4.Systemic illness which affects bone metabolism.
5.Extreme skeletal Class II malocclusion, Overjet > 10mm.
6.Not willing for informed consent.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of the rate of orthodontic tooth movement in high frequency & low frequency vibrations.	6 months
Effect of high frequency vibrations & low frequency vibrations in rate of orthodontic tooth movement.	6 months

Secondary Outcome Measures

Name	Time	Method
Effects of mechanical vibrations on root resorption.	6 months

Trial Locations

Locations (1): Subharti Dental College and Hospital
🇮🇳
Meerut, UTTAR PRADESH, India
Subharti Dental College and Hospital
🇮🇳Meerut, UTTAR PRADESH, India
Dr Akhil Anton Joy
Principal investigator
9497282341
akhilantonjoy@gmail.com