Immune Response and Cytomegalovirus in Intensive Care Unit (ICU) Patients
Not Applicable
Completed
- Conditions
- Cytomegalovirus Infection
- Interventions
- Other: Sampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markings
- Registration Number
- NCT00699868
- Lead Sponsor
- Assistance Publique Hopitaux De Marseille
- Brief Summary
This prospective study evaluate the immune status of patients admitted in ICU.CMV remains dormant in the body, but in people with immune deficiency, CMV could reactivate and cause life-threatening pneumonia.
- Detailed Description
Candidates will be screened with medical history and blood tests.Then, 2 groups of 20 patients (with or without CMV reactivation) matched for CMV status will be compared for their immune system against CMV.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 29
Inclusion Criteria
- Age more than 18-year-old
- Informed consent
Exclusion Criteria
- minors,
- pregnant or lactating women,
- adults under guardianship,
- immunosuppression at the entrance to resuscitation,
- AIDS
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 1 Sampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markings Infection to CMV 2 Sampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markings Group "control CMV"
- Primary Outcome Measures
Name Time Method Bring to light the quantitative and qualitative immunological modifications of the present cells NK before the arisen of an infection to CMV 24 months
- Secondary Outcome Measures
Name Time Method Bring to light the quantitative and qualitative immunological modifications of cells NK in the consequences of an infectious shock 24 months
Trial Locations
- Locations (1)
Hôpital de Sainte Marguerite- Service de Réanimation Médicale
🇫🇷Marseille, France