Effects of pentoxyfilline diabetic nephropathy
Phase 3
Recruiting
- Conditions
- diabetic nephropathy.Type 2 diabetes mellitus with diabetic nephropathyE11.21
- Registration Number
- IRCT20121104011356N10
- Lead Sponsor
- ational Institute for Medical Research Development
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
type2 diabetes according to American Diabetes Association (ADA 2019)
with proteinuria
Exclusion Criteria
infectious or malignant diseases
non-diabetic kidney disease
retinal hemorrhage
acute myocardial infarction or unstable angina
history of cardio-cerbro-vascular or peripheral artery disease
uncontrolled hypertension (i.e., systolic blood pressure [SBP] = 140mmHg and/or diastolic blood pressure [DBP] = 90 mmHg)
pregnancy
anemia
hyperthyroidism
history of hemodialysis
baseline serum potassium concentrations =5.5 meq/L
estimated glomerular filtration rate (eGFR) < 30mL/minute/1.73 m and pentoxifylline intolerance
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method