Effect of pentoxifylline on proteinuria of diabetic patients
Phase 4
- Conditions
- Diabetes Mellitus.Non-insulin-dependent diabetes mellitus, type II
- Registration Number
- IRCT201010144941N1
- Lead Sponsor
- Babol University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 54
Inclusion Criteria
diabetics type 2 with proteinuria more than 500 mg /d under treatment with ACEI for at least 3 months
Exclusion criteria: diabetics type 1, creatinin more than 1.5 mg/dl, systolic blood pressure more than 140 mmHg, Patients on hemodialysis, presence of fever, acute respiratory distress, or acute heart failure, non- diabetic proteinuric glomerulopathies, obstructive urinary stones, confirmed hypersensitivity to caffeine, theophylline or pentoxifylline, recent brain or retinal hemorrhage, recent 3 months use of thiazolidinediones
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proteinuria. Timepoint: before and after intervention. Method of measurement: 24 hours urinary protein measurment.
- Secondary Outcome Measures
Name Time Method Serum creatinine. Timepoint: Before and after the intervention. Method of measurement: serum cratinine measurement by jaffe method.