Feasibility of contrast enhanced ultrafast ultrasound to determine aortoiliac blood flow

Completed

• Conditions: Het betreft hier een pilot studie voor gezonde proefpersonen, uiteindelijk zal deze techniek op het gebied van bloedvataandoeningen worden toegepast; stenotic vessels; vessel calcicifation

• Registration Number: NL-OMON42877
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-03-24
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

healthy, slim (BMI below 22), willingness to undergo MRI scan, willingness to undergo echoPIV examination

Exclusion Criteria

* Hypersensitivity to the active substance(s) or any of the excipients in SonoVue
* Right-to-left cardiac shunt
* Severe pulmonary hypertension (pulmonary artery pressure > 90mmHg)
* Uncontrolled systemic hypertension
* Pregnancy
* Lactation
* Participation in another clinical trial within 3 months prior to the experimental day
* The standard MRI exclusion criteria (pacemakers, cerebral vascular clips, pregnancy, claustrophobia)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>To determine the feasibility of high framerate CEUS in deep arterial<br /><br>structures, in this case the distal aorta, to obtain blood flow velocities over<br /><br>the longitudinal section of the vessel lumen. If feasibility is proven a<br /><br>patient study will be planned, including patients treated for AIOD.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Correlation of high speed CEUS with MRI phase contrast data to validate the<br /><br>obtained results<br /><br>Determine near wall accuracy of obtained velocities.<br /><br>Determine needed amount of contrast to obtain good quality data</p><br>