Impact of Human Papillomavirus Carriage on IVF/ICSI Results at Brest University Hospital
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 618
- 试验地点
- 1
- 主要终点
- clinical pregnancy rate after fresh eSET by HPV status
研究概览
简要总结
The prevalence of the papilloma virus in the general population is 12%. This virus is known to impair male fertility but its impact on female infertility remains uncertain. This is a public health problem since there is a vaccination protocol. Demonstrating the impact of the human papillomavirus on fertility would be an argument in favor of vaccination.
详细描述
This is a single-center prospective study in the assisted reproduction center of Brest University Hospital. All new patients coming to consult will be offered participation in the study. The HPV test will be updated if it is older than 12 months. We will analyze stimulation results and pregnancy outcomes according to HPV status. Inclusions will take place over 3 years
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 25 Years 至 38 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •all etiology of infertility AMH > ou = à 1.1 ng/ml First ou second protocol of IVF between 25 years and 37 years and 11 months
排除标准
- •Age < 25 y Age > ou = 38 y AMH < 1.1 ng/ml patient under juridic protection rejection of participation
结局指标
主要结局
clinical pregnancy rate after fresh eSET by HPV status
时间窗: 1 year
A clinical pregancy is the visualisation of a gestational sac inside the uterus after 6 weeks of gestation
次要结局
- Positive HPV rate(1 year)
- IVF issues(1 year)