Estudo Longitudinal de Saúde do Adulto
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 15,105
- 主要终点
- Myocardial infarction (Incident cases)
研究概览
简要总结
The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) aims to contribute with relevant information regarding the development and progression of clinical and subclinical chronic diseases, particularly cardiovascular diseases and diabetes. The investigators enrolled 15,105 civil servants from predefined universities or research institutes. Baseline assessment (2008-2010) included detailed interviews and measurements to assess social and biological determinants of health, as well as various clinical and subclinical conditions related to diabetes, cardiovascular diseases and mental health. For the ascertainment of incident events, annual telephone surveillance is being conducted since 2009, and a second visit of interviews and exams is under way (2012-2014). Long-term biological sample storage is provided for sera, plasma, urine and DNA. Baseline data is available for analyses, and collaboration via specific research proposals directed to study investigators is welcome.
This multicenter study is chaired by a steering committee, made up of the coordinators and vice-coordinators of each of the six centers. No individual center coordinates the study. The six institutions listed in the contact details all sponsor the study.
详细描述
Full details of the study have been published in the American Journal of Epidemiology (http://aje.oxfordjournals.org/content/early/2012/01/10/aje.kwr294.full) and the International Journal of Epidemiology (http://ije.oxfordjournals.org/content/early/2014/02/27/ije.dyu027.abstract), as listed in the References here. Both articles are available in full text for download without charge.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 35 Years 至 74 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 35-74 years,
- •active or retired employees of the institutions involved or affiliated institutions.
排除标准
- •current or recent (<4 months prior to the first interview) pregnancy,
- •intention to quit work at the institution in the near future,
- •severe cognitive or communication impairment and,
- •if retired, residence outside each center´s corresponding metropolitan area.
结局指标
主要结局
Myocardial infarction (Incident cases)
时间窗: 6 years
Incident cases
Diabetes mellitus (Incident cases)
时间窗: 6 years
Incident cases
次要结局
未报告次要终点
研究者
MSchmidt
Associate Professor
Federal University of Rio Grande do Sul