Germ Cell Tumor and Testicular Tumor DNA Registry
概览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,000
- 试验地点
- 8
- 主要终点
- creation of a Germ Cell Tumor and testicular tumor registry
概览
简要总结
This study is being done to create a registry to help us learn more about germ cell tumors (GCT) and other testicular tumors. The registry will include people with these tumors and also relatives and unrelated people without these tumors. This study will help us learn more about the prevention, diagnosis, treatment and outcome of these tumors. Studying relatives of patients and people unrelated to patients with GCT and other testicular tumors will help us understand why some people get these tumors and why some people don't.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Case Cohort
- •Must be ≥ 18 years of age AND
- •Must be an English-speaker AND
- •Must have a diagnosis or suspicion of germ cell tumor and/or a testicular mass
- •Family Member Cohort
- •Must be ≥ 18 years of age AND
- •Must be an English-speaker AND
- •Must be a blood relative of the proband. Family members of probands are eligible. These individuals need not have a diagnosis of GCT-TT, as they will be used for segregation analysis of suspected variants found in the proband.
- •Control Cohort
- •Must be ≥ 18 years of age AND
排除标准
- 未提供
研究组 & 干预措施
A: suspicion of germ cell tumor and/or a testicular mass
patients with testicular GCTs and non-GCT testicular tumors, extragonadal male GCTs, and female GCTs,
干预措施: Questionnaires (Behavioral)
A: suspicion of germ cell tumor and/or a testicular mass
patients with testicular GCTs and non-GCT testicular tumors, extragonadal male GCTs, and female GCTs,
干预措施: sample of blood or saliva (Other)
B: family members of Group A
relatives of patients with GCTs or testicular tumors
干预措施: Questionnaires (Behavioral)
B: family members of Group A
relatives of patients with GCTs or testicular tumors
干预措施: sample of blood or saliva (Other)
C: healthy controls unrelated to Group A or B
healthy controls who are unrelated to Groups A or B and do not have a personal history of cancer nor a family history of GCT or non-GCT testicular tumors
干预措施: Questionnaires (Behavioral)
C: healthy controls unrelated to Group A or B
healthy controls who are unrelated to Groups A or B and do not have a personal history of cancer nor a family history of GCT or non-GCT testicular tumors
干预措施: sample of blood or saliva (Other)
结局指标
主要结局
creation of a Germ Cell Tumor and testicular tumor registry
时间窗: 5 years
We will collect clinical data including diagnosis date, pathology, family history, and risk factors in patients with GCT-TT.
次要结局
未报告次要终点