Assessement of the effects of coffee main constituents (caffeine and chlorogenic acid) supplementation on inflammatory, metabolic factors, hepatic steatosis and fibrosis in none- alcoholic fatty liver patients with type 2 diabetes

IMAD0 个研究点目标入组 100 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

暂无简介。

•Inclusion Criteria:
•Patient diagnosed with type 2 diabetes based on American Diabetes Association (ADA) definition or who only take oral antidiabetic drug.
•CAPscore >263

•Taking any kind of antibiotics two weeks before recruitment;
•History of alcohol consumption ;
•pregnancy or lactation;
•Professional athletes;
•Other liver disease (viral/etc);
•High dose synthetic estrogens, methotrexate , amiodarone, steroids, chloroquine, immunosuppressive drugs;
•A history of Cardiovascular disease;
•Renal disease, Celiac disease, Cirrhosis;
•History of Upper Gastrointestinal surgery ;
•A history of hypothyroidism or Cushing's syndrome;
•History of drug dependence;
•Body mass index (BMI) =35 kg/m2;
•A restrictive diet or weight change = 5 kg during the 3 months prior to study;
•Any change in treatment with oral hypoglycemic; anti hypertensive and antilipid agents during the study;
•Use of weight loss medications

发起方

IMAD