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Real World Study of Lapatinib Among Metastatic Breast Cancer Patients

Completed
Conditions
Breast Cancer
Registration Number
NCT03894410
Lead Sponsor
Fudan University
Brief Summary

A multicenter, retrospective, real world study of Lapatinib among Metastatic Breast Cancer (MBC) Patients in Clinical Practice.

Detailed Description

This study collected patients used Lapatinib-base therapy among MBC, and tried to figure out if there was difference between single anti-Her2 treatment and dual anti-Her2 treatment. Furthermore, this study investigated the treatment after Lapatinib.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
242
Inclusion Criteria
  • Patients who were treated with Lapatinib between June 2014 to June 2018.
  • Patients experienced progression on prior trastuzumab-containing regimens and a taxane.
  • Complete medical history was available.
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Exclusion Criteria
  • Medical history was incomplete.
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Number of participants with treatment-related adverse events as assessed by Common Terminology Criteria for Adverse Events version 4.0 (CTCAE v4.0)6 weeks
PFS6 weeks

Progression free survival

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Fudan University Shanghai Cancer Center

🇨🇳

Shanghai, Shanghai, China

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