Radiation Therapy Plan Quality Improvement Using Ideal Theoretical Isodose Distribution

Not Applicable

Completed

• Conditions: Head and Neck Neoplasms

• Registration Number: NCT04782726
• Lead Sponsor: The University of Texas Health Science Center at San Antonio

Brief Summary

The researchers hope that based on the study findings future patients may benefit from a more precise radiation treatment plan that can be developed more quickly and thus decrease the time from Computerized Tomography Simulation to start of treatment.

Detailed Description

As part of this study participants will receive the standard of care treatment for all head and neck cancer patients. The researchers plan to use a software program to see if it will assist in developing the best radiation treatment plan possible. The researchers will also measure the quality of each treatment plan so areas of improvement can be identified.

Study Timeline

• Study First Submitted: 2021-03-01
• Study First Submitted QC: 2021-03-01
• Study First Posted: 2021-03-04
• Study Start: 2021-12-16
• Status Verified: 2023-01
• Primary Completion: 2023-01-20
• Study Completion: 2023-01-20
• Last Update Submitted: 2023-01-20
• Last Update Posted: 2023-01-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

• Age ≥ 18 years.
• Ability to provide informed written consent in either English or Spanish.
• Patient planned to undergo radiation therapy for Head and Neck Cancer.

Exclusion Criteria

• Current pregnancy, as this is a contraindication to receiving radiation therapy.
• History of prior radiotherapy to the head and neck.
• Any condition or history as evidenced by patient record and/or self-report that, in the opinion of the investigator, would interfere with adherence to daily radiation therapy.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Mean radiation dose to Organs at Risk (OAR)	Baseline to last treatment (up to 33 treatments or about 7 weeks)	Measurement of radiation dose to organs at risk. The goal is to maintain the PTV (Planning Target Volume) coverage while minimizing the dose to organs at risk (OARs).
Maximum radiation dose to Organs at Risk (OAR)	Baseline to last treatment (up to 33 treatments or about 7 weeks)	Measurement of maximum radiation dose to organs at risk. The goal is to maintain the PTV (Planning Target Volume) coverage while minimizing the dose to organs at risk (OARs).

Secondary Outcome Measures

Name	Time	Method
Time required to plan radiation therapy dose	CT Simulation to first treatment (about 1 week)	The time required with and without individualized pre optimization information will be recorded and compared to determine efficiency.

Trial Locations

Locations (1)

Mays Cancer Center; 🇺🇸 San Antonio, Texas, United States