ULTRASOUND BASED MEASURES OF INFERIOR VENA CAVA VERSUS INTERNAL JUGULAR VEIN FOR PREDICTION OF HYPOTENSION IN PATIENTS UNDER GENERAL ANESTHESIA

Not yet recruiting

• Conditions: Abnormal findings on diagnostic imaging of other body structures,

• Registration Number: CTRI/2023/05/052403
• Lead Sponsor: DEPARTMENT OF ANESTHESIOLOGY

Brief Summary

Hypotension following the induction of general anesthesia is common in routine practice. Intravenous anesthetic agents cause cardiovascular depression and reduction in peripheral sympathetic tone resulting in vasodilator effect causing hypotension. However , all these factors become even more significant in Hypovolemic patients. Therefore, assessing the intravascular volume before Anesthesia plays a key role in preventing or minimising such hypovolemic events. Ultrasonography measurements of  Inferior vena cava(IVC) and Internal jugular vein (IJV) with respiration can be used to determine the intravascular volume. So, the patients will be divided into two groups -

Group A - In this group of patients, ultrasound based diameters of IVC is to be measured to check the accuracy of IVCCI for predicting post induction hypotension.

Group B - In this group of patients, ultrasound based diameters of IJV is to be measured to check the accuracy of IJVCI for predicting post induction hypotension

Then general anesthesia will be administered and systolic blood pressure (SBP), Diastolic blood pressure (DBP), Mean Blood pressure(MBP), and Heart rate (HR) will be noted till 20 minutes after endotracheal intubation.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-15
• Last Update Posted: 2023-09-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 172

Inclusion Criteria

1)Patients aged 18-60 years’ old 2)Any scheduled non-cardiac surgery under general anaesthesia 3)AMERICAN SOCIETY OF ANAESTHESIOLOGIST(ASA) Physical Status I and II.

Exclusion Criteria

• 1)Patients with major vascular disease 2)Unstable angina 3)Ejection fraction <40% 4)Respiratory distress 5)Increased Intra-abdominal pressure.
• 6)Implanted pacemaker.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of sensitivity and specificity of IVC and IJV variations in prediction of post-induction hypotension.	Comparison of sensitivity and specificity of IVC and IJV variations in prediction of post-induction hypotension.

Secondary Outcome Measures

Name	Time	Method
To analyse the changes in the following parameters	a) Heart Rate

Trial Locations

Locations (1)

KALINGA INSTITUTE OF MEDICAL SCIENCES; 🇮🇳 Khordha, ORISSA, India

KALINGA INSTITUTE OF MEDICAL SCIENCES

🇮🇳Khordha, ORISSA, India

SANJEEV TRIPATHI

Principal investigator

8133823209

tripathisanjeev355@gmail.com