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临床试验/CTRI/2023/05/052403
CTRI/2023/05/052403尚未招募不适用

COLLAPSIBILITY INDEX OF INFERIOR VENA CAVA VERSUS INTERNAL JUGULAR VEIN FOR PREDICTION OF HYPOTENSION DURING INDUCTION OF GENERAL ANESTHESIA

DEPARTMENT OF ANESTHESIOLOGY1 个研究点 分布在 1 个国家目标入组 172 人开始时间: 2023年5月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
172
试验地点
1
主要终点
Comparison of sensitivity and specificity of IVC and IJV variations in prediction of post-induction hypotension.

研究概览

简要总结

Hypotension following the induction of general anesthesia is common in routine practice. Intravenous anesthetic agents cause cardiovascular depression and reduction in peripheral sympathetic tone resulting in vasodilator effect causing hypotension. However , all these factors become even more significant in Hypovolemic patients. Therefore, assessing the intravascular volume before Anesthesia plays a key role in preventing or minimising such hypovolemic events. Ultrasonography measurements of  Inferior vena cava(IVC) and Internal jugular vein (IJV) with respiration can be used to determine the intravascular volume. So, the patients will be divided into two groups -

Group A - In this group of patients, ultrasound based diameters of IVC is to be measured to check the accuracy of IVCCI for predicting post induction hypotension.

Group B - In this group of patients, ultrasound based diameters of IJV is to be measured to check the accuracy of IJVCI for predicting post induction hypotension

Then general anesthesia will be administered and systolic blood pressure (SBP), Diastolic blood pressure (DBP), Mean Blood pressure(MBP), and Heart rate (HR) will be noted till 20 minutes after endotracheal intubation.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients aged 18-60 years’ old 2)Any scheduled non-cardiac surgery under general anaesthesia 3)AMERICAN SOCIETY OF ANAESTHESIOLOGIST(ASA) Physical Status I and II.

排除标准

  • Patients with major vascular disease 2)Unstable angina 3)Ejection fraction <40% 4)Respiratory distress 5)Increased Intra-abdominal pressure.
  • Implanted pacemaker.

结局指标

主要结局

Comparison of sensitivity and specificity of IVC and IJV variations in prediction of post-induction hypotension.

时间窗: Comparison of sensitivity and specificity of IVC and IJV variations in prediction of post-induction hypotension.

次要结局

  • To analyse the changes in the following parameters(a) Heart Rate)

研究者

申办方类型
Private medical college

研究点 (1)

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