EUCTR2013-003307-20-IT
Active, Not Recruiting
N/A
Sedation Practices in Intensive Care Evaluation: SPICE III – A Prospective Multicentre Randomised Controlled Trial of Early Goal Direct Sedation vs. Standard Care Sedation”
ANZIC RESEARCH CENTRE0 sites4,000 target enrollmentOctober 22, 2013
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- ANZIC RESEARCH CENTRE
- Enrollment
- 4000
- Status
- Active, Not Recruiting
- Last Updated
- 11 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\-age over 18 years;
- •\-patient intubated and subjected to mechanical ventilation;
- •\-patient to high likelihood of mechanical ventilation for more than 24 hours (unlikely extubating the following day);
- •\-patient requiring immediate sedation for the management of his/her comfort, security, and to facilitate the intensive treatment
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range 100
- •F.1\.3 Elderly (\>\=65 years) yes
- •F.1\.3\.1 Number of subjects for this age range 100
Exclusion Criteria
- •\-Patient under the age of 18 years;
- •\-Patient intubated for more than 12 hours in an ICU (excluding any operating room time or transport);
- •\-acute injury certain or suspected primary acute brain barrier, such as head trauma, intracranial hemorrhage, brain injury, stroke or hypoxia;
- •\-death is considered imminent or inevitable during hospitalization;
Outcomes
Primary Outcomes
Not specified
Similar Trials
Active, Not Recruiting
Phase 4
Early sedation with dexmedetomidine vs. placebo in older ventilated critically ill patientsISRCTN37114000Cardiff and Vale University Health Board3,500
Not Yet Recruiting
Phase 4
Early Sedation With Dexmedetomidine vs. Placebo in Older Ventilated Critically Ill PatientsRespiratory InsufficiencyNCT06251375St. Joseph's Healthcare Hamilton300
Completed
Phase 3
Effect of Dexmedetomidine on patient's sedation and surgeon's satisfaction during wisdom tooth surgeryIRCT20200406046966N1Esfahan University of Medical Sciences26
Completed
N/A
Recording the level of analgesia in intensive care patients - is the measurement of the RIII-reflex a useful addition to the established categorical pain detection scales in non-communicative patients?Detection of the nociceptive flexor reflex in the analgosedated intensive care patientIncidence of deliriumMortality ratesAssessment of the thresholds in different subgroupsDRKS00021149Klinik für Anästhesiologie - Interdisziplinäre Operative Intensivmedizin144
Active, Not Recruiting
N/A
Sedation during routine procedural sedation in the pediatric intensive care unit - clinical vs. technical measurement of sedation depthdepth of sedationDRKS00024075niversitätsklinikum EssenKlinik für Kinderheilkunde I23