Transfusion of plasma to ABO not matched transplant patients.
Not Applicable
- Conditions
- Health Condition 1: C920- Acute myeloblastic leukemia
- Registration Number
- CTRI/2022/10/046554
- Lead Sponsor
- JIPMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ABO-incompatible hematopoietic transplant recipients
Exclusion Criteria
1.Donors plasma with no SAS (non secretors)
2.Donors who are tested positive for transfusion transmissible infection
Donor - Department of Transfusion medicine
Patient - Medical oncology department
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the change in anti-A anti-B antibody titre levels before and after transfusion of donor plasma having A and B secretary substances in ABO incompatible hematopoietic transplant recipientsTimepoint: Within 24 hours of intervention
- Secondary Outcome Measures
Name Time Method To identify the clinical factors associated with change in anti-A, anti-B titres in ABO incompatible transplant recipients following AB donor plasma transfusion. <br/ ><br> <br/ ><br>Timepoint: Immediately after intervention within 24 hours and 4 weeks