Comparison of Average volume assured pressure support (AVAPS) and standard bilevel modes of non invasive ventilation in childre

Not Applicable

Recruiting

• Conditions: Hypoventilation; Respiratory - Sleep apnoea; Neurological - Other neurological disorders; Musculoskeletal - Other muscular and skeletal disorders

• Registration Number: ACTRN12618000084280
• Lead Sponsor: Sydney Children's Hospital Network

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-01-19
• Last Update Posted: 10 February 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Clinical evidence of need for non invasive ventilation
Adherence to standard care
Stable clinical status

Exclusion Criteria

Acute respiratory failure
Unstable haemodynamically or co-existing respiratory condition eg Cystic Fibrosis.
Respiratory illness within 4 weeks of initial titration
Unwilling or unable to adhere to non invasive ventilation
Tracheostomy
Rapidly progressive neurological disorder in which the respiratory impairment would deteriorate rapidly over 12months eg SMA type 1

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in polysomnography parameters -Transcutaneous CO2 (TcCO2) change from baseline. Transcutaneous CO2 monitor attached throughout polysomnograph[Compare to baseline and 3 months post initiation of each mode of ventilation]