Outcome of multimodal periarticular injection with corticosteroid for better pain management in total knee arthroplasty: A randomized controlled trial
Completed
- Conditions
- Post-operative pain after total knee arthroplastyPainVASTKASteroidPeriarticular injection
- Registration Number
- TCTR20211216004
- Lead Sponsor
- none
- Brief Summary
The study found significantly lower pain score (VAS) in steroid group compared to control group at postoperative day 1 7am (VAS 1.73 +/-0.63 vs 2.18 +/- 1.09, respectively 95%CI -0.09 to 0.99 p-value 0.099) and postoperative day 3 2pm (VAS 1.59 +/- 0.85 vs 2.23 +/- 0.69, respectively 95%CI 0.17 to 1.11 p-value 0.0093). Steroid group performed faster straight leg raise and ambulation. Shorter hospital stays were observed without any significant adverse outcome.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 22
Inclusion Criteria
patient age 40 - 80 years diagnosed with OA knee and eligible for unilateral primary total knee arthroplasty
Exclusion Criteria
Poor controlled DM HbA1C > 8
ESRD
Other inflammatory arthritis
Immunocompromised host
Allergic to drug in trial
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain score post-operative day 1,2 and 3 VAS
- Secondary Outcome Measures
Name Time Method Time to straight leg raise, post-operatively post-operative day 1,2 and 3 hour,Time to ambulation, post-operatively post-operative day 1,2 and 3 hour,Adverse outcome of corticosteroid injection 1 month visit percentage of infection or tendon rupture