Toothpaste With Sodium Carbonate in Patients With Gingivitis
- Conditions
- GingivitisPeriodontal Diseases
- Interventions
- Drug: Toothpaste Product
- Registration Number
- NCT06224699
- Lead Sponsor
- University of Catania
- Brief Summary
Sodium carbonate has several properties that may be beneficial in the management of bacterial biofilm in gingivitis patients. The aim of this RCT study is to clinically evaluate the clinical properties of two toothpaste containing Sodium carbonate 67% and fluoride toothpaste that contains no bicarbonate on patients with gengivitis.
- Detailed Description
Sodium carbonate has several properties that may be beneficial in the management of bacterial biofilm in both gingivitis and periodontitis patients. The aim of this RCT study is to clinically evaluate the clinical properties of two toothpaste containing sodium carbonate at 67% or no sodium carbonate at 67% at 6-month follow-up in patients with gingivits. The study was designed as a double-blind randomized controlled trial (RCT) with 2 parallel groups of individuals.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 44
- Clinically diagnosed with gingivitis according to the EFP/AAP 2017 criteria.
- Periodontal treatment, antibiotics, NSAIDs, immunosuppressants during the last 6 months.
- Pregnancy.
- Systemic diseases.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Test group Toothpaste Product Use of toothpaste with sodium carbonate 67% Control Toothpaste Product Use of toothpaste without sodium carbonate 67%
- Primary Outcome Measures
Name Time Method Gingival index (1-4) 6-months Gingival index reduction
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
AOU Policlinico Catania
🇮🇹Catania, Italy