Chinese Medicine in combination with western medicine for the prevention of relapse in patients with severe psoriasis

Phase 1

• Conditions: Psoriasis

• Registration Number: ITMCTR2000003295
• Lead Sponsor: Guangdong Hospital of traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. The patients with psoriatic lesions area and severity index PASI = 10 met the diagnostic criteria of severe psoriasis;
2. Patients who meet the indications of biological agents (iqizhu) and have no history of inflammatory bowel disease (IBD);
3. Patients who sign informed consent.

Exclusion Criteria

Psoriasis patients not suitable for iqizhu treatment.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time to relapse;

Secondary Outcome Measures

Name	Time	Method
Body Surface Area;The proportion of patients who achieve at least 90% improvement in PASI score from baseline;Skindex16;Dermatology Life Quality Index (DLQI);The improvement in PASI score from baseline after treatment;The proportion of patients who achieve at least 75% improvement in PASI score from baseline;Physician's global assessment (PGA) score;Pruritus Scores on the Visual Analogue Scale;