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Study of effects of vitamin D on some genes expression in multiple sclerosis patients

Not Applicable
Conditions
Multiple sclerosis.
Multiple sclerosis
Registration Number
IRCT2014081818840N1
Lead Sponsor
Vice Chancellor forTarbiat Modares University of Tehran
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
45
Inclusion Criteria

relapsing-remitting multiple sclerosis patients; MS patients with vitamin D deficiency (<80ng/ml). Exclusion criteria: patients treated with vitamin D supplements; progressive MS; relapsed patients, psychiatric patients and the patients who are taken steroid drugs.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Expression of IL2 gene. Timepoint: before vitamin D treatment and two month after treatment. Method of measurement: taking of blood from patients and measurment of mRNA level.
Secondary Outcome Measures
NameTimeMethod
Expression of IL4 ,IL6,IL17A,CYP27A1 and CYP27B1. Timepoint: before vitamin D treatment and two month after treatment. Method of measurement: taking of blood from patients and measurement of mRNA level.
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