Examining Different Modes of Exercise for Acute Reduction in Blood Pressure

Not Applicable

Completed

• Conditions: Hypertension
• Interventions: Behavioral: Exercise; Behavioral: Resting

• Registration Number: NCT06628635
• Lead Sponsor: University of Saskatchewan

Brief Summary

The purpose of the study is to compared different modes of exercise for eliciting post-exercise hypotension. The study will randomize 10 healthy participants to 30 minutes of either aerobic exercise, isometric exercise, stretching, or rest (control). Blood pressure and heart rate will be assessed before and for one hour post-exercise.

Detailed Description

The purpose is to compare different modes of exercise (aerobic vs. isometric vs. static stretching) for reducing blood pressure post-exercise. : Using a randomized crossover design, 5 male and 5 female (n=10) normotensive university students will participate in four different exercise sessions for 30 minutes: aerobic (cycle ergometer at 70% of VO2max), isometric (alternating wall-sit for 70% of max, and handgrip dynamometer at 30% of max for 2 minutes), stretching (targeting the larger muscle groups of the body), and control (rest). Participants' blood pressure and heart rate will be measured before each exercise session and monitored for 60 minutes afterwards to analyze the post-exercise hypotensive response.

Study Timeline

• Study Start: 2024-01-04
• Primary Completion: 2024-04-10
• Study Completion: 2024-04-15
• Status Verified: 2024-10
• Study First Submitted: 2024-10-03
• Study First Submitted QC: 2024-10-04
• Last Update Submitted: 2024-10-04
• Study First Posted: 2024-10-07
• Last Update Posted: 2024-10-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Able to safely perform exercise according to the Get Active Questionnaire

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Exclusion Criteria

• Taking blood pressure medications

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Aerobic exercise	Exercise	30 minutes of moderate-intensity aerobic exercise on a cycle ergometer
Isometric exercise	Exercise	30 minutes of isometric exercise (alternating hand-grip with wall-sitting)
Static stretching	Exercise	30 minutes of static stretching of major muscle groups
Resting control	Resting	30 minutes of seated rest

Primary Outcome Measures

Name	Time	Method
Change in systolic blood pressure (mmHg)	Baseline to 60 minutes after exercise
Change in diastolic blood pressure (mmHg)	Baseline to 60 minutes after exercise

Secondary Outcome Measures

Name	Time	Method
Change in heart rate (beats per minute)	Baseline to 60 minutes after exercise
Change in rate-pressure product (beats per mintues x systolic blood pressure mmHg)	Change from baseline to 60 minutes after exercise

Trial Locations

Locations (1)

University of Saskatchewan; 🇨🇦 Saskatoon, Saskatchewan, Canada