Post- Rotatory Nystagmus Test: Normative Data for Spanish Adolescents and Adults

• Conditions: Vestibular Function Tests; Nystagmus Vestibular

• Registration Number: NCT04788134
• Lead Sponsor: Quesada, Rocío Vico

Brief Summary

The vestibulo-ocular reflex is the motor response of our eyes in the opposite direction to a translational or rotational movement of our head. The post-rotational nystagmus test (PRN) assesses the integrity of this reflex, thus assessing the perception of the vestibular system. The duration of this reflex after administering this test has been widely studied in children from 2 months to 12 years and 11 months of age. However, there is a knowledge gap from that age that the present study seeks to address.

Detailed Description

The vestibulo-ocular reflex (VOR) is the motor response of our eyes in the opposite direction to a translational or rotational movement of our head. The post-rotational nystagmus test (PRN) assesses the integrity of this reflex, thus assessing the perception of the vestibular system. This system has an important role in our balance, stabilization of the visual field when our head moves, awareness of the position of our head in space, postural control and functions of the Autonomous Nervous System.

The duration of this reflex after administering this test has been widely studied in children from 2 months to 12 years and 11 months of age. However, there is a knowledge gap from that age that the present study seeks to address. This article aims to explore the use of the PRN test for adolescent and adults, to prove if the duration of the VOR is longer in these population than in children. It will be also recollected personal data to study whether exposure to vestibular input influences its reactivity and perception.

Study Timeline

• Status Verified: 2021-03
• Study First Submitted: 2021-03-04
• Study First Submitted QC: 2021-03-08
• Last Update Submitted: 2021-03-08
• Study First Posted: 2021-03-09
• Last Update Posted: 2021-03-09
• Study Start: 2021-04-01
• Primary Completion: 2021-06-01
• Study Completion: 2021-09-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 163

Inclusion Criteria

• People over 13 years of age.
• Spanish-speaking population.
• Signature of the informed consent.

Exclusion Criteria

• Diagnosis of a neurodevelopmental or neurological disorder.
• Being in occupational therapeutic treatment for balance or vestibular problems.
• Practice of sports in one previous hour.
• Adverse reaction to vestibular input such as vomiting, discoloration, feeling of unpleasantness or any other type of negative reaction before / during / after the administration of the NPR.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration of vestibular-ocular reflex after the administration of nystagmus post-rotatory test in adolescent and adult population	End of the nystagmus post rotatory test and end of the vestibular-ocular reflex	The post rotatory nystagmus test evaluates the duration of the vestibular-ocular reflex: how long its lats gives information about the perception of vestibular system. This reflex reflects the role of the vestibular system in ocular mechanisms (Mailloux et al., 2014). It is administered twice: clockwise and counterclockwise.After the administration the physiologic nystagmus appears, it is our vestibular-ocular reflex, and the examiner has to register the duration of it.