Construction and Evaluation of Clinical Prediction Model of In-stent Restenosis After Percutaneous Coronary Intervention by Pericoronary Fat Attenuation Index and Radiomics Characteristics
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- RenJi Hospital
- Enrollment
- 126
- Locations
- 1
- Primary Endpoint
- Fat attenuation index (FAI)
Study Overview
Brief Summary
This study aims to investigate the predictive value of fat attenuation index (FAI) and related radiomics characteristics of pericoronary fat in patients after percutaneous coronary intervention (PCI) for the occurrence of in-stent restenosis (ISR) during the follow-up period (9 to 24 months). The results of this study are expected to provide an early assessment of the inflammation around the coronary lesion segment in patients after PCI, and provide a basis for early targeted intensive drug therapy in clinical practice.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients with coronary heart disease who have undergone PCI;
- •Patients followed up coronary angiography 9 to 24 months after PCI;
- •Patients received chest CT examination during inpatient/outpatient follow-up;
Exclusion Criteria
- •Patients with diseases of the immune system;
- •Patients with history of tumor diseases;
- •Patients with chronic/acute infectious diseases;
- •Image quality is not sufficient for analysis;
Outcomes
Primary Outcomes
Fat attenuation index (FAI)
Time Frame: 2022.8.15-2023.8.14
The pericoronary FAI was defined as the mean CT attenuation of the pericoronary adipose tissue (-190 to -30 HU). Peri-stent FAI was measured around the stent segment of all 3 major epicardial coronary vessels.
Secondary Outcomes
No secondary outcomes reported