Volume Responsiveness Before SBT Predicts the Outcome of Mechanical Ventilation Weaning in Critically Ill Patients

Completed

• Conditions: Weaning Failure
• Interventions: Device: PLR

• Registration Number: NCT01867853
• Lead Sponsor: Southeast University, China

Brief Summary

To evaluate the performance of volume responsiveness in predicting the outcome of mechanical ventilation weaning in critically ill patients.

Detailed Description

82 patients, 61 succeed and 21 failed

Study Timeline

• Study Start: 2012-10
• Primary Completion: 2013-03
• Study Completion: 2013-03
• Study First Submitted: 2013-05-06
• Study First Submitted QC: 2013-05-29
• Status Verified: 2013-06
• Last Update Submitted: 2013-06-03
• Study First Posted: 2013-06-04
• Last Update Posted: 2013-06-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 82

Inclusion Criteria

• mechanical ventilation

Exclusion Criteria

• pregnancy or breast-feeding
• tracheostomy at baseline
• myasthenia gravis or acute polyradiculoneuropathy
• end-stage chronic illness

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
successful weaning	PLR	the SUCCESS of SBT or not need for reintubation or noninvasive ventilation within 48 h following extubation
failed weaning	PLR	the failure of SBT or the need for reintubation or noninvasive ventilation within 48 h following extubation

Primary Outcome Measures

Name	Time	Method
changes of cardiac index	30 minutes

Trial Locations

Locations (1)

Zhongda hospital; 🇨🇳 Nanjing, Jiangsu, China