Analgesic action of acetaminophen in symptomatic osteoarthritis of the knee: a randomised controlled study
Completed
- Conditions
- Osteoarthritis of the kneeMusculoskeletal DiseasesOsteoarthritis
- Registration Number
- ISRCTN14751911
- Lead Sponsor
- Merck Sharp and Dohme (MSD) (Switzerland)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Patients and healthy subjects: 20 patients fulfilled the American College of Rheumatology criteria for knee OA accompanied with joint pain (visual analogue scale [VAS] =60) were recruited to the study. For control, blood from 20 age and gender-matched healthy subjects was obtained from a local blood bank, the Blutspenderdienst Zürich. All patients signed the informed consent.
Exclusion Criteria
1. Secondary OA as a consequence of inflammation, gout, pseudogout or tumour
2. Kidney insufficiency
3. OA-influencing concomitant diseases
4. Drug medication with opioids
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method