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Clinical and Radio-graphic Evaluation of Non-staining Bio-active Bio-ceramic (Neo MTA 2) in Revascularization

Phase 2
Not yet recruiting
Conditions
Mineral Trioxide Aggregate
Interventions
Drug: NeoMTA2
Drug: WMTA
Registration Number
NCT06637761
Lead Sponsor
Cairo University
Brief Summary

The study will compare the clinical and radio-graphic performance of newly introduced non-staining bio-active bio-ceramic (Neo MTA 2) versus White MTA used as coronal plug material in revascularization of non-vital immature permanent anterior teeth.Visual examination, palpation, A measuring scale in digital radio-graph software (DIGORA for Windows software) will be used for evaluation.

Detailed Description

Mineral trioxide aggregate (MTA) has been widely used in revascularization procedures for coronal sealing in more than 85% of studies for privilege of bio compatibility, good sealing properties, and marginal adaptation. However, its poor handling characteristics and potential coronal discoloration effects are the major disadvantages of using mineral trioxide aggregate.

Although white MTA (WMTA) has been developed to overcome the tooth discoloration caused by the application of grey MTA, several in vivo and in vitro studies have also reported tooth discoloration after using WMTA.

To overcome the problems associated with WMTA, a new modification was introduced to the market called NeoMTA 2 as a new hope to overcome the discoloration problem. NeoMTA 2 provides easier handling, shorter setting time, and better color. The lack of post-operative discoloration problems was mainly due to the absence of Bismuth oxide in NeoMTA.

up to date, no clinical trials have reported the clinical and radio-graphic outcomes after revascularization of non-vital immature permanent anterior teeth using Neo MTA 2. Thus, the present study aims to evaluate and compare clinically and radio-graphically the effect of using two different coronal plug materials (Neo MTA 2 versus White mineral trioxide aggregate) in revascularization of non-vital immature permanent anterior teeth.

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
22
Inclusion Criteria
  • Cooperative patient/ compliant parents or guardians
  • Patients free from any systemic diseases that hinder the normal healing process according to parental history
  • Necrotic immature permanent anterior teeth
  • Enough coronal portion of teeth that does not necessitate post and core for final restoration
Exclusion Criteria
  • Patients having an allergy to medicament and antibiotics necessary to complete the procedure
  • Teeth with internal or external root resorption
  • Uncooperative patients/ in-compliant parents or guardians
  • Laxative injuries
  • Avulsed tooth after re-plantation
  • Compromised remaining coronal structure

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Group INeoMTA2NeoMTA 2 Manipulation and mixing will be done according to manufacturer instructions: * 1 scoop (0.1gm) of NeoMTA 2 Powder will be dispensed on a glass slab. Then two drops of NeoMTA 2 Gel will be dispensed next to the powder. * Gradually as much Gel as necessary will be added to the Powder to achieve the desired consistency. The Gel will be incorporated by spatula-ting the Powder/Gel mixture firmly against the glass slab to ensure all of the Powder is thoroughly witted by the Gel.
Group IIWMTAWhite mineral trioxide aggregate * One spoon of powder and one drop of distilled water are dispensed on a sterile glass slab. * A metal spatula will be used to gradually mix the liquid and powder together for 30 seconds to ensure full wetting of the powder particles and to obtain a consistency similar to wet sand. * 3-4 mm of white MTA will be placed over the clot carefully by using an amalgam carrier. The mix will be placed over the collagen matrix 2mm beneath the clinical cement-enamel junction.
Primary Outcome Measures
NameTimeMethod
Discoloration1 year

Using shade guide (VITA classical)

Secondary Outcome Measures
NameTimeMethod
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