Combination therapy with azelnidipine or trichlormethiazide added on olmesartan in hypertensive patients with glucose intolerance

Not Applicable

• Conditions: Hypertension with glucose intolerance

• Registration Number: JPRN-UMIN000003459
• Lead Sponsor: Kanazawa Medical University Diabetes & Endocrinology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-04-07
• Study Completion: 2011-11-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Not provided

Exclusion Criteria

1)Among patients on azelnidipine or trichlormethiazide 2)Severe hepatic disease 3)Severe renal disease(During dialysis) 4)pregnancy or possibility of the pregnancy 5)posses hypersensitivity to azelnidipine or trichlormethiazide 6)Patients with insulin treatment or scheduling the insulin administration 7)FBS 100mg/dl moreover HbA1c 5.2 moreover 8)Patients who are inadequate to entry this study by physians in charge

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Insulin sensitivity

Secondary Outcome Measures

Name	Time	Method
Changes in blood pressure level at home after gettin up. Aggravation of the renal function. changes in urinary albumin level,albuminuria,eGFR. hsCRP,8-OHDG,uric acid,K, new onset of diabetes.