Conditioning Regimen Before Infusion of Allogeneic Hematopoietic Stem Cells
Completed
- Conditions
- HEMATOLOGIC MALIGNANCIES
- Registration Number
- NCT00770523
- Lead Sponsor
- Cooperative Study Group A for Hematology
- Brief Summary
Unrelated Donor Hematopoietic Stem Cell Transplantation After Nonmyeloablative Conditioning for Younger Patients with Hematologic Malignancies.
- Detailed Description
Primary end points are treatment-related mortality and engraftment. Secondary end points are regimen-related toxicities, graft-versus-host-disease, relapse, and overall survival.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
-Patients should have an unrelated donor who is matched for HLA-A and -B by serology and for -DRB1 by molecular typing.
Exclusion Criteria
- Patients should not have major illness or organ failure
- Patients must not have a psychiatric disorder or mental deficiency severe as to make compliance with the treatment unlike, and making informed consent impossible.
- Patients must not be pregnant or lactating.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method treatment-related mortality and engraftment all cause mortality
- Secondary Outcome Measures
Name Time Method regimen-related toxicities, graft-versus-host-disease, relapse, and overall survival. Time point(s) at which outcome measure is assessed.
Trial Locations
- Locations (1)
Asan Medical Center
🇰🇷Seoul, Korea, Republic of