The comparison of positive pressure delivered at the end of expiration administered by a supra glottic airway device with no positive pressure delivered on severity of lung collapse during/after surgery under anaesthesia
Phase 4
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/08/056277
- Lead Sponsor
- All India Institute Of Medical Sciences New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients 18-65 years of age
Both male, female
ASA I and II
Posted for elective lower abdominal and urological surgery will be included
Exclusion Criteria
Patients less than 18years and more than 65 years of age
ASA III and IV
Patients with any lung disease
Patients with cardiac disease
Obesity BMI >30 Kg/m2
Pregnancy
Anaemia Hb <7 g/dl
Anticipated difficult airway
Patients posted for laproscopic upper abdominal surgeries will be excluded
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the loss of lung aeration (atelectasis) as measured by modified lung ultrasound score between the PEEP (8cm H2O) and No PEEP group.Timepoint: A: Baseline, before induction of anesthesia <br/ ><br>B: 10 minutes following induction of general anesthesia <br/ ><br>C: 1 hour following induction of general anesthesias <br/ ><br>D: 30 minutes after removal of PLMA <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1.Gas leakage around the Proseal LMA(PLMA) <br/ ><br>2.Peak inspiratory pressure (PIP) and dynamic compliance <br/ ><br>3.PaO2/FiO2 ratio <br/ ><br>4.Displacement or malpositioning of the PLMATimepoint: 1. Gas leakage will be determined built-in leakage detection system of ventilator and presence of audible gas leakage at 5min,30min and 60min after insertion of PLMA <br/ ><br>2. The PIP and dynamic compliance (C-dy) will be noted from the ventilator at 5min and 30min after device insertion. <br/ ><br>3. PaO2/FiO2(P/F) ratio will be noted at baseline, 1 hour following induction of general anesthesia and 30min postoperatively by obtaining arterial blood samples. <br/ ><br> <br/ ><br>