Impact of different positive end-expiratory pressure (PEEP) with low tidal volumes during one-ventilation on lung mechanics, gas exchange, and hemodynamics
Not Applicable
Recruiting
- Conditions
- Onel-lung ventilation
- Registration Number
- DRKS00004247
- Lead Sponsor
- Zentralklinik Bad BerkaKlinik für Anästhesie und Intensivemdizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 276
Inclusion Criteria
Thoracic Surgery
Onelung ventilation
Exclusion Criteria
Lack of informed consent
Incapability to give informed consent
Severe impairment of pulmonary function (<75%)
Previous partial lung resection
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Oxygenation after 30 min one-lung ventilation measured by arterial pO2 in the blood gas analysis
- Secondary Outcome Measures
Name Time Method Dynamic compliance during one-lung ventilation calculated from the parameters of mechanical ventilation,<br>Ventilation during one-lung ventilation measured by arterial pCO2 in the blood gas analysis,<br>Frequency of clinically significant hypoxemia (necessity to apply CPAP or two-lung ventilation)