Efficacy of Zinc in the Treatment of Pneumonia in Hospitalized Children Less Than 2 Years of Age
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 299
- Primary Endpoint
- Duration of severe symptoms
Study Overview
Brief Summary
This study is designed to evaluate the efficacy of zinc supplementation in the treatment of children under the age of two years who have been hospitalized with severe pneumonia.
Detailed Description
This study was a randomized, double-blind, placebo-controlled clinical trial conducted between September 2003 and August 2004 at the Christian Medical College (CMC) Hospital in Vellore, India. CMC Hospital is a large teaching hospital and medical center that is accessed directly by the population of Vellore and adjoining districts and by referrals from local medical practitioners.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Investigator)
Eligibility Criteria
- Ages
- — to 23 Months (Child)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •children under two years old hospitalized with Pneumonia
Exclusion Criteria
- •healthy children
Arms & Interventions
Treatment
Children with severe pneumonia were randomly assigned to receive supplementation with elemental zinc.
Intervention: Zinc (Drug)
Outcomes
Primary Outcomes
Duration of severe symptoms
Time Frame: 2 years
Secondary Outcomes
- Time to recovery from severe pneumonia(2 years)
Investigators
Mathuram Santosham
Professor
Johns Hopkins Bloomberg School of Public Health