Compare the Analgesic Effect of Different Anesthesia and Postoperative Analgesic Methods in Uniportal VATS Lung Surgery
试验速览
- 阶段
- 1 期
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- visual analogue scale（VAS）
研究概览
简要总结
This is a single center, randomized, single blind study to compare the analgesic effect of different anesthesia and postoperative analgesic methods in uniportal VATS lung surgery.
详细描述
Combining epidural with general anesthesia is regarded as the gold standard of general thoracic surgery. The uniportal VATS lung surgery have advantages of minimal invasive surgical incision, less postoperative pain, and so on. Whether general anesthesia can become an alternative method of combining epidural with general anesthesia in uniportal VATS lung surgery, investigators thus plan to make a comparison on intraoperative stress response, postoperative pain, immune function of patients，and hospital expenses.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients elective uniportal VATS lung surgery;
- •BMI 18-30 kg/m2.
排除标准
- •Patient refuse;
- •Patients allergic to use anesthetics (propofol,rocuronium), patients with liver and/or kidney and/or mental dysfunction.
研究组 & 干预措施
general anesthesia group
The patients in this group receive general anesthesia preoperatively, and use patient controlled intravenous analgesia postoperatively.
干预措施: general anesthesia (Combination Product)
epidural group
The patients in this group receive general anesthesia combined with epidural anesthesia, and use patient controlled epidural analgesia postoperatively.
干预措施: epidural anesthesia (Combination Product)
结局指标
主要结局
visual analogue scale（VAS）
时间窗: 1 year
This scale mainly reflects the patient's pain
次要结局
未报告次要终点