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Clinical Trials/NCT04690985
NCT04690985
Completed
Not Applicable

Dietary Behaviour Change Intervention on Managing Sarcopenic Obesity in Community-dwelling Older People: a Feasibility and Pilot Study

The Hong Kong Polytechnic University1 site in 1 country60 target enrollmentJuly 1, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sarcopenic Obesity
Sponsor
The Hong Kong Polytechnic University
Enrollment
60
Locations
1
Primary Endpoint
Changes of body weight
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The aim of this study is to evaluate the feasibility and preliminary effects of dietary behavior change intervention on the management of sarcopenic obesity (SO) among older people in the community.

The feasibility and preliminary effects of the intervention will be tested using a two-armed pilot randomized controlled trial among older people (N=60) with SO in the community in Nanjing, China. Finally, 10 participants will be invited to join a semi-structured interview to explore their perceptions about the whole intervention process.

It is hypothesized that the experimental group will have a greater improvement in the body composition, muscle strength and physical function compared to the control group after receiving the 15-week dietary behavior change intervention.

Detailed Description

The pilot study is a single-blind, two-arm randomized controlled trial. A total of 60 subjects (60 years old or more) are planned to be recruited. The subjects will be randomly divided into 2 groups witht a ratio of 1:1. One is the experimental group and the other is the control group. The experimental group will receive 15 weeks of dietary intervention, including 6 face-to-face meetings and weekly telephone call. Each meeting lasts for 1 hour. The participants in the experimental group are required to control of calorie intake (decrease energy intake by 12%) and increase protein intake (1.2-1.5 g/body weight kg/day), and take dietary diary. The control group will not receive any dietary interventions. They will only receive regular contacts with a similar frequency as the experimental group. The content of the conversations will not involve any topics related to SO. After the intervention, 10-15 people from the experimental group will be randomly selected to receive semi-structured individual interview, which will last around 1 hour. The researcher plan to understand their feelings about participating in the study.

Registry
clinicaltrials.gov
Start Date
July 1, 2020
End Date
February 28, 2021
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dr. Justina Liu Yat Wa

Associate Professor

The Hong Kong Polytechnic University

Eligibility Criteria

Inclusion Criteria

  • community-dwelling older people aged 60 years old or above;
  • handgrip strength \< 28 kg for men and \< 18 kg for women;
  • BMI ≥ 28% or waist circumference ≥ 85 cm in men and ≥ 80 cm in women;
  • be able to read and write without severe hearing and vision problems.

Exclusion Criteria

  • suffering from severe heart disease or metabolic disorders (e.g. renal diseases, diabetes) or autoimmune disease, cancer, or any other diseases/ conditions which may affect food intake and digestion or amputee;
  • cognitively impaired (e.g. dementia) may impede the delivery of the intervention;
  • under special diet restriction such as on diabetes disease diet, vegetarian, ketogenic diet, etc.;
  • using of medications that may influence eating behavior, digestion or metabolism (such as weight loss medication);
  • addicted to alcohol;
  • a metal device is implanted in the body;
  • be engaged in another trials.

Outcomes

Primary Outcomes

Changes of body weight

Time Frame: Change from baseline to 1 week after the programme

Body weight (kg) will be measured.

Changes of physical function

Time Frame: Change from baseline to 1 week after the programme

The Short Physical Performance Battery (SPPB) scale will be used to measure physical function, which is a well-established tool for monitoring function in older people, which contains three kinds of assessments: stand for 10 seconds with feet in 3 different positions, 3-meter or 4-meter walking speed test, and time to rise from a chair for five times. The scores of SPPB range from 0 (worst performance) to 12 (best performance).

Changes of visceral fat score

Time Frame: Change from baseline to 1 week after the programme

Visceral fat score will be measured by using bioelectrical impedance analysis. Maintain a visceral fat score below 10 means good health.

Recruitment rate

Time Frame: Baseline

The proportion of participants who consent to join the study over the eligible participants.

Changes of skeletal muscle mass

Time Frame: Change from baseline to 1 week after the programme

Skeletal muscle mass (kg) will be measured by using bioelectrical impedance analysis.

Changes of muscle strength

Time Frame: Change from baseline to 1 week after the programme

Handgrip strength (kg) will be measured by using the jamar dynamometer.

Adherence to diet regimen

Time Frame: Throughout the 15-week programme

Diet adherence will be assessed by the session attendance (Rate of attendance in 6 sessions).

Occurrence of adverse events

Time Frame: Throughout the 15-week programme

Any adverse events at home will be recorded.

Changes of fat mass

Time Frame: Change from baseline to 1 week after the programme

Fat mass (kg) will be measured by using bioelectrical impedance analysis.

Changes of body mass index

Time Frame: Change from baseline to 1 week after the programme

The weight and height will be combined to report BMI in kg/m\^2.

Changes of percentage of body fat

Time Frame: Change from baseline to 1 week after the programme

Percentage of body fat will be reported by the percent of body fat mass in whole body weight.

Changes of waist-to-hip ratio

Time Frame: Change from baseline to 1 week after the programme

Waist circumference(cm) and hip circumference (cm) will be measured to report the waist-to-hip ratio.

Attrition rate

Time Frame: At the end of the 15-week programme

The percentage of participants who withdraw from the study and their reasons for withdrawing.

Secondary Outcomes

  • Nutrition Self-efficacy Scale(Change from baseline to 1 week after the programme)
  • Dietary quality index-International(Change from baseline to 1 week after the programme)
  • Mini Nutritional Assessment (MNA) Short-form(Change from baseline to 1 week after the programme)
  • Short Form Health Survey (SF-36)(Change from baseline to 1 week after the programme)
  • International Physical Activity Questionnaire Short-form (IPAQ-SF)(Change from baseline to 1 week after the programme)

Study Sites (1)

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