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临床试验/NCT05478460
NCT05478460已完成不适用

Acute and Chronic Pain After Video-assisted Thoracoscopic Surgery for Lung Cancer in Patients With Preoperative CT-guided Hookwire Localization

Fudan University1 个研究点 分布在 1 个国家目标入组 161 人开始时间: 2021年8月10日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
161
试验地点
1
主要终点
postoperative incidence and intensity of chronic pain after surgery

研究概览

简要总结

The aim of this study is to evaluate whether preoperative CT- guided hookwire localization would influence the incidence and intensity of acute and chronic pain after VATS.

详细描述

Postoperative pain after thoracic surgery has gained recognition as a adverse outcome and head-scratching problem. The incidence of choric postoperative pain (CPSP) in thoracic surgery has been reported to be 20%-80%. However, there has been not an standard treatment for CPSP. Many study has showed the risk factors of CPSP in thoracic surgery, such as VATS type, operation time, duration of drainage, preoperative pain, repeat surgery, gender, postoperative chemotherapy or radiation therapy , etc. It is important that moderate-to-severe acute postoperative pain will be transformed into CPSP. That offers a new management goal in postoperative pain prevention.CT-guided hookwire localization have been proven to be benefical for VATS to diagnose and treat small pulmonary , it can shorten operation timing and increase surgery success rate. However, it causes roughly 23.8% severe pain and complaints included wire dislodgement, pneumothorax and haemorrhage during and after insertion. The question is whether or not the moderate-to-severe acute postoperative pain from hookwire localition will change the incidence and intensity of CPSP in VATS.

Nurses play a pivotal role in advanced practice, research, and education in the field of pain management. The pain management of hookwire localization may be a new vison in further research.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Aged 18-75
  • patients who underwent underwent CT-guided localization before VATS
  • BMI 18.5-30
  • no serious complications after localization
  • sign informed consent

排除标准

  • could not complish underwent CT-guided localization
  • selfexpression or visual dysfunction
  • having emergency surgery
  • a severe psychiatric illness
  • having chronic pain problems in the chest area
  • Pregnant women

结局指标

主要结局

postoperative incidence and intensity of chronic pain after surgery

时间窗: at postoperative 6th month

the incidence and severity(11-point numerical rating scale, 0=painless, 10=worst pain)of pain was assessed after VATS operation

次要结局

  • postoperative length of stay in hospital(an average of 1 week)
  • satisfactory score(from the day discharge from hospital to postoperative 6th month)
  • intensity of postoperative acute pain(from immediately after surgery(at postanesthesia care unit ) to postoperative 2nd day)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jun Zhang

chairman of Department of Anesthesiology

Fudan University

研究点 (1)

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