Acute and Chronic Pain After Video-assisted Thoracoscopic Surgery for Lung Cancer

Completed

• Conditions: Lung Cancer
• Interventions: Other: Hookwire localization

• Registration Number: NCT05478460
• Lead Sponsor: Fudan University

Brief Summary

The aim of this study is to evaluate whether preoperative CT- guided hookwire localization would influence the incidence and intensity of acute and chronic pain after VATS.

Detailed Description

Postoperative pain after thoracic surgery has gained recognition as a adverse outcome and head-scratching problem. The incidence of choric postoperative pain (CPSP) in thoracic surgery has been reported to be 20%-80%. However, there has been not an standard treatment for CPSP. Many study has showed the risk factors of CPSP in thoracic surgery, such as VATS type, operation time, duration of drainage, preoperative pain, repeat surgery, gender, postoperative chemotherapy or radiation therapy , etc. It is important that moderate-to-severe acute postoperative pain will be transformed into CPSP. That offers a new management goal in postoperative pain prevention.CT-guided hookwire localization have been proven to be benefical for VATS to diagnose and treat small pulmonary , it can shorten operation timing and increase surgery success rate. However, it causes roughly 23.8% severe pain and complaints included wire dislodgement, pneumothorax and haemorrhage during and after insertion. The question is whether or not the moderate-to-severe acute postoperative pain from hookwire localition will change the incidence and intensity of CPSP in VATS.

Nurses play a pivotal role in advanced practice, research, and education in the field of pain management. The pain management of hookwire localization may be a new vison in further research.

Study Timeline

• Study Start: 2021-08-10
• Study First Submitted: 2022-05-30
• Primary Completion: 2022-07-21
• Study Completion: 2022-07-21
• Study First Submitted QC: 2022-07-25
• Study First Posted: 2022-07-28
• Status Verified: 2022-10
• Last Update Submitted: 2022-10-21
• Last Update Posted: 2022-10-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 161

Inclusion Criteria

• Aged 18-75
• patients who underwent underwent CT-guided localization before VATS
• ASA I-II
• BMI 18.5-30
• no serious complications after localization
• sign informed consent

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Exclusion Criteria

• could not complish underwent CT-guided localization
• selfexpression or visual dysfunction
• having emergency surgery
• a severe psychiatric illness
• having chronic pain problems in the chest area
• Pregnant women

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group A	Hookwire localization	Before operation,patients were performed CT -guided hook wire localization(20G×120mm, PAJUNK medizintechnologie, Geisingen in Germany). patients were placed on a CT table in a suitable position(supine, prone, lateral) to obtain the shortest needle insertion route for their initial CT scan. Local anesthesia of the skin and planned puncture tract was performed using 10ml Lidocaine 1%. Next, the needle was inserted into or near the pulmonary nodule.

Primary Outcome Measures

Name	Time	Method
postoperative incidence and intensity of chronic pain after surgery	at postoperative 6th month	the incidence and severity（11-point numerical rating scale, 0=painless, 10=worst pain）of pain was assessed after VATS operation

Secondary Outcome Measures

Name	Time	Method
postoperative length of stay in hospital	an average of 1 week	the days between postoperative 1st day and day of discharge from hospital
satisfactory score	from the day discharge from hospital to postoperative 6th month	Likert score (from 1 to 5),higher scores mean a better outcome
intensity of postoperative acute pain	from immediately after surgery(at postanesthesia care unit ) to postoperative 2nd day	the severity(11-point numerical rating scale, 0=no pain, 10=worst pain) after VATS operation

Trial Locations

Locations (1)

270 Dongan Road, Fudan University Shanghai Cancer Center; 🇨🇳 Shanghai, China