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Clinical Trials/NCT05478460
NCT05478460
Completed
Not Applicable

Acute and Chronic Pain After Video-assisted Thoracoscopic Surgery for Lung Cancer in Patients With Preoperative CT-guided Hookwire Localization

Fudan University1 site in 1 country161 target enrollmentAugust 10, 2021
ConditionsLung Cancer

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Lung Cancer
Sponsor
Fudan University
Enrollment
161
Locations
1
Primary Endpoint
postoperative incidence and intensity of chronic pain after surgery
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The aim of this study is to evaluate whether preoperative CT- guided hookwire localization would influence the incidence and intensity of acute and chronic pain after VATS.

Detailed Description

Postoperative pain after thoracic surgery has gained recognition as a adverse outcome and head-scratching problem. The incidence of choric postoperative pain (CPSP) in thoracic surgery has been reported to be 20%-80%. However, there has been not an standard treatment for CPSP. Many study has showed the risk factors of CPSP in thoracic surgery, such as VATS type, operation time, duration of drainage, preoperative pain, repeat surgery, gender, postoperative chemotherapy or radiation therapy , etc. It is important that moderate-to-severe acute postoperative pain will be transformed into CPSP. That offers a new management goal in postoperative pain prevention.CT-guided hookwire localization have been proven to be benefical for VATS to diagnose and treat small pulmonary , it can shorten operation timing and increase surgery success rate. However, it causes roughly 23.8% severe pain and complaints included wire dislodgement, pneumothorax and haemorrhage during and after insertion. The question is whether or not the moderate-to-severe acute postoperative pain from hookwire localition will change the incidence and intensity of CPSP in VATS. Nurses play a pivotal role in advanced practice, research, and education in the field of pain management. The pain management of hookwire localization may be a new vison in further research.

Registry
clinicaltrials.gov
Start Date
August 10, 2021
End Date
July 21, 2022
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jun Zhang

chairman of Department of Anesthesiology

Fudan University

Eligibility Criteria

Inclusion Criteria

  • Aged 18-75
  • patients who underwent underwent CT-guided localization before VATS
  • BMI 18.5-30
  • no serious complications after localization
  • sign informed consent

Exclusion Criteria

  • could not complish underwent CT-guided localization
  • selfexpression or visual dysfunction
  • having emergency surgery
  • a severe psychiatric illness
  • having chronic pain problems in the chest area
  • Pregnant women

Outcomes

Primary Outcomes

postoperative incidence and intensity of chronic pain after surgery

Time Frame: at postoperative 6th month

the incidence and severity(11-point numerical rating scale, 0=painless, 10=worst pain)of pain was assessed after VATS operation

Secondary Outcomes

  • postoperative length of stay in hospital(an average of 1 week)
  • satisfactory score(from the day discharge from hospital to postoperative 6th month)
  • intensity of postoperative acute pain(from immediately after surgery(at postanesthesia care unit ) to postoperative 2nd day)

Study Sites (1)

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