Three-armed study for therapy of primary and secondary syphilis in HIV infectio
Phase 4
- Conditions
- A53.9Syphilis, unspecified
- Registration Number
- DRKS00000389
- Lead Sponsor
- St. Josef HospitalInterdisziplinäre Immunologische Ambulanz
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 115
Inclusion Criteria
HIV positive Patients with serologically proven early syphilis
Exclusion Criteria
-known sensibilization agaist ß-lactam antibiotics
-patients that were treated within the last 48h with an agent that is active against treponema pallidum
-pregnant or lactating women
-patients with late syphilis (latent syphilis of unknown duration, tertiary syphilis or neuro syphilis
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method treatment failure defined as:<br>-retreatment or<br>-treatment with any antibiotic active against treponema pallidum or<br>-no reduction by 2 titer levels in VDRL or FTAabs19S IgM after 48 weeks
- Secondary Outcome Measures
Name Time Method