COMBINED SUBSTITUTIVE THERAPY WITH LEVOTHYROXINE AND LIOTHYRONINE IN THYROIDECTOMIZED PATIENTS: EFFECTS ON PERIPHERICAL TISSUES. A PROSPECTIVE RANDOMIZED CONTROLLED DOUBLE BLIND STUDY. - LEVOLIO

AZIENDA UNITÀ SANITARIA LOCALE DI MODENA0 个研究点目标入组 260 人开始时间: 2018年1月3日最近更新: 2018年1月8日

适应症

试验速览

暂无简介。

•Patients older than 18, capable of consent, able to sign a written informed consent, able to understand and fill in an italian questionnaire; residual thyroid function nearly absent (thyroidectomized, with serum tireoglobulin < 0.2 ng/ml and negative anti-tireoglobulin antibodies , in order to avoid methodological measurement interference), well comopensated with LT4 (pills)substitutive therapy, at stable dose for at least 3 months.
•Are the trial subjects under 18? no
•Number of subjects for this age range: 1
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 200
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 60

•TSH-suppressive therapy, pregnancy, severe cardiac diseases, pituitary or adrenal untreated insufficiency, severe liver or kidney or bone disease, ongoing therapy with corticosteroids, amiodarone, colestiramine or iron, or with anti-absorptive drugs ongoing or in the previous 12 months, alcohol addiction, epilepsy.

发起方

AZIENDA UNITÀ SANITARIA LOCALE DI MODENA